First human test of gene therapy for rare muscle disease begins

NCT ID NCT05230459

Summary

This study is testing the safety of a single-dose gene therapy called AB-1003 in adults with limb-girdle muscular dystrophy type 2I/R9, a rare genetic muscle disorder. Researchers will give increasing doses to small groups of participants to check for side effects. The goal is to see if this experimental treatment is safe enough for further testing.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

Locations

  • Kennedy Krieger Institute

    RECRUITING

    Baltimore, Maryland, 21205, United States

    Contact

    Contact Email: •••••@•••••

  • University of California - Irvine

    RECRUITING

    Irvine, California, 92697, United States

    Contact

    Contact Email: •••••@•••••

  • University of Iowa

    RECRUITING

    Iowa City, Iowa, 52242, United States

    Contact Email: •••••@•••••

    Contact

  • University of Kansas Medical Center

    RECRUITING

    Kansas City, Kansas, 66160, United States

    Contact Email: •••••@•••••

    Contact

  • University of Washington Medical Center

    RECRUITING

    Seattle, Washington, 98195, United States

    Contact

    Contact Email: •••••@•••••

  • VCU

    RECRUITING

    Richmond, Virginia, 23298, United States

    Contact Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.