One-Shot gene therapy aims to free hemophilia patients from lifelong injections

NCT ID NCT01687608

Summary

This early-stage trial is testing a single injection of gene therapy for adults with hemophilia B. The goal is to see if the treatment is safe and if it can help the body produce its own missing clotting factor, potentially reducing or eliminating the need for regular injections. The study will enroll up to 16 men to test different dose levels.

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Contacts and locations

Locations

  • BloodCenter of Wisconsin

    Milwaukee, Wisconsin, 53226, United States

  • Bloodworks Northwest

    Seattle, Washington, 98104, United States

  • Children's Hospital Los Angeles

    Los Angeles, California, 90027, United States

  • Children's Hospital of Boston

    Boston, Massachusetts, 022105, United States

  • Emory University

    Atlanta, Georgia, 30322, United States

  • Gulf States Hemophilia and Thrombosis Center

    Houston, Texas, 77030, United States

  • Medical University of South Carolina

    Charleston, South Carolina, 29425, United States

  • Mount Sinai Medical Center

    New York, New York, 10029, United States

  • Orthopaedic Hemophilia Treatment Center

    Los Angeles, California, 90007, United States

  • Rush University Medical Center

    Chicago, Illinois, 60612, United States

  • The Hemophilia Center, Oregon Health and Science University

    Portland, Oregon, 97239, United States

  • U of Colorado School of Medicine, Hemophilia & Thrombosis Treatment Center

    Aurora, Colorado, 80045, United States

  • University of California Davis Medical Center

    Sacramento, California, 95817, United States

  • University of California at San Diego Medical Center

    San Diego, California, 92103-8651, United States

  • University of Minnesota, Masonic Clinical Research Unit, Clinical and Translational Science Institute

    Minneapolis, Minnesota, 55455, United States

Conditions

Explore the condition pages connected to this study.