Silencing genes to fight liver scarring: new trial targets serious fatty liver disease

NCT ID NCT05519475

Recruiting now Disease control Sponsor: Regeneron Pharmaceuticals Source: ClinicalTrials.gov ↗

Summary

This study is testing an experimental drug designed to 'silence' a specific gene involved in a serious form of fatty liver disease called MASH. The goal is to see if the drug can reduce liver inflammation and scarring (fibrosis) in adults with MASH who have certain genetic risk factors. About 90 participants will be randomly assigned to receive either the study drug or a placebo to compare the effects.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Adobe Clinical Research
RECRUITING

Tucson, Arizona, 85712, United States
Advanced Medical Trials
RECRUITING

Georgetown, Texas, 78628, United States
Allure Health at Mt. Olympus Medical Research
TERMINATED

Friendswood, Texas, 77546, United States
American Research Corporation
RECRUITING

Austin, Texas, 78757, United States
American Research Corporation at The Texas Liver Institute
RECRUITING

San Antonio, Texas, 78215, United States
Arizona Liver Health
RECRUITING

Chandler, Arizona, 85224, United States
Arizona Liver Health - Tucson
RECRUITING

Tucson, Arizona, 85712, United States
Ark Clinical Research - Fountain Valley
RECRUITING

Fountain Valley, California, 92708, United States
Ark Clinical Research - Long Beach
RECRUITING

Long Beach, California, 90815, United States
Austin Clinical Research, LLC
TERMINATED

Austin, Texas, 78745, United States
Cadena Care Inst.
TERMINATED

Poway, California, 92064, United States
California Liver Research Institute
RECRUITING

Pasadena, California, 91105, United States
Charter Research LLC - Orlando
RECRUITING

Orlando, Florida, 32803, United States
Clinnova Research Solutions
RECRUITING

Orange, California, 92868, United States
Columbia University Irving Medical Center
RECRUITING

New York, New York, 10032, United States
Deaconess Clinic - GI Specialty Center
RECRUITING

Newburgh, Indiana, 47630, United States
Del Sol Research Management, LLC
RECRUITING

Tucson, Arizona, 85715, United States
Evolution Clinical Trials
RECRUITING

Hialeah Gardens, Florida, 33016, United States
Fundacion de Investigacion (FDI) Clinical Research
RECRUITING

San Juan, 00927, Puerto Rico
GI Alliance Research
RECRUITING

Fort Worth, Texas, 76104, United States
GI Associates
RECRUITING

Flowood, Mississippi, 39232, United States
Geisinger Medical Center
RECRUITING

Danville, Pennsylvania, 17822, United States
Genoma Research Group, Inc.
RECRUITING

Miami, Florida, 33173, United States
Great Lakes Research Institute
TERMINATED

Pharr, Texas, 78577, United States
Hanyang University Seoul Hospital
TERMINATED

Seoul, 04763, South Korea
Health Awareness, inc.
RECRUITING

Jupiter, Florida, 33458, United States
Indiana University School of Medicine
RECRUITING

Indianapolis, Indiana, 46202, United States
Inland Empire Liver Foundation
RECRUITING

Rialto, California, 92377, United States
Intermountain Health
RECRUITING

Murray, Utah, 84107, United States
International Medical Investigational Centers (IMIC) Incorporated
TERMINATED

Miami, Florida, 33157, United States
Isis Clinical Research Center
TERMINATED

Guaynabo, San Juan, 00969, Puerto Rico
JCHO Hokkaido Hospital
TERMINATED

Sapporo, Hokkaido, 062-8618, Japan
Keimyung University Dongsan Hospital
TERMINATED

Daegu, 42601, South Korea
Klinical Investigations
TERMINATED

San Juan, 00909, Puerto Rico
Knowledge Research Center, St. Joseph's Medical Tower
RECRUITING

Orange, California, 92868, United States
Kyungpook National University Hospital
TERMINATED

Daegu, 41944, South Korea
Latin Clinical Trial Center
TERMINATED

San Juan, 00909, Puerto Rico
Med Research of Florida, LLC
RECRUITING

Miami, Florida, 33186, United States
Mercy Medical Center
TERMINATED

Baltimore, Maryland, 21202, United States
Methodist Dallas Medical Center
RECRUITING

Dallas, Texas, 75203, United States
Miami Clinical Research
TERMINATED

Miami, Florida, 33155, United States
National Research Institute
TERMINATED

Panorama City, California, 91402, United States
Om Research Llc
RECRUITING

Lancaster, California, 93534, United States
Penn State Health Milton S. Hershey Medical Center
RECRUITING

Hershey, Pennsylvania, 17033, United States
Pinnacle Clinical Research - Austin
RECRUITING

Austin, Texas, 78757, United States
Pinnacle Clinical Research - San Antonio
RECRUITING

San Antonio, Texas, 78229, United States
Pioneer Research Solutions, Inc.
RECRUITING

Houston, Texas, 77099, United States
Precision Research Institute - San Diego
TERMINATED

San Diego, California, 92114, United States
Pusan National University Hospital
TERMINATED

Busan, 49241, South Korea
R & H Clinical Research
TERMINATED

Stafford, Texas, 77477, United States
R & H Clinical Research, Inc.
TERMINATED

Katy, Texas, 77494, United States
Richmond Veterans Administration Medical Center
RECRUITING

Richmond, Virginia, 23249, United States
San Fernando Valley Health Institute
TERMINATED

Canoga Park, California, 91304, United States
Seoul National University Bundang Hospital
TERMINATED

Seongnam-si, Gyeonggi-do, 13620, South Korea
South Texas Research Institute (STRI) - Brownsville
RECRUITING

Brownsville, Texas, 78520, United States
South Texas Research Institute (STRI) - Edinburg
RECRUITING

Edinburg, Texas, 78539, United States
Southern California Research Center
RECRUITING

Coronado, California, 92118, United States
Synergy Healthcare LLC
TERMINATED

Bradenton, Florida, 34209, United States
Tandem Clinical Research
RECRUITING

Metairie, Louisiana, 70006, United States
The Institute for Liver Health II LLC DBA Arizona Clinical Trials - Flagstaff
TERMINATED

Flagstaff, Arizona, 86001, United States
The Institute for Liver Health II LLC DBA Arizona Liver Health - Peoria
RECRUITING

Peoria, Arizona, 85381, United States
US Associates in Research, LLC
TERMINATED

Miami, Florida, 33175, United States
University of Colorado Anschutz Medical Campus
RECRUITING

Aurora, Colorado, 80045, United States
University of Pennsylvania - Perelman Center for Advanced Medicine
RECRUITING

Philadelphia, Pennsylvania, 19104, United States
University of Virginia Medical Center
RECRUITING

Charlottesville, Virginia, 22903, United States
Velocity Clinical Research
TERMINATED

Chula Vista, California, 91911, United States
Velocity Clinical Research
TERMINATED

Gardena, California, 90247, United States
Velocity Clinical Research - Austin
TERMINATED

Cedar Park, Texas, 78613, United States
Velocity Clinical Research - Huntington Park
TERMINATED

Huntington Park, California, 90255, United States
Velocity Clinical Research - Westlake
TERMINATED

Los Angeles, California, 90057, United States
Washington University School of Medicine
RECRUITING

St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.

METABOLIC DYSFUNCTION ASSOCIATED STEATOHEPATITIS (MASH)