First-of-its-Kind gene editing trial aims to cure devastating immune disease

NCT ID NCT06959771

Summary

This study is testing a new gene therapy for a single patient with a rare and serious inherited immune disorder called CD40L-HyperIgM syndrome. Doctors will use a precise gene-editing tool to fix the patient's own blood stem cells and immune cells, then infuse them back after a mild chemotherapy. The goal is to permanently correct the genetic error, restore a healthy immune system, and cure the disease.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.