New gene therapy approach for sickle cell disease moves to safety testing

NCT ID NCT03664830

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 29 times

Summary

This early-stage study tests whether a drug called plerixafor can safely collect enough stem cells from people with sickle cell disease for a future gene therapy. Five participants will receive up to two injections of plerixafor. The goal is to see if this method is safe and works well enough to move forward with gene therapy.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • City of Hope Medical Center

    Duarte, California, 91010, United States

Conditions

Explore the condition pages connected to this study.