Gene therapy could cut eye injections for wet AMD patients
NCT ID NCT05197270
First seen Nov 01, 2025 · Last updated May 02, 2026 · Updated 30 times
Summary
This study tests a gene therapy called 4D-150 for people with wet age-related macular degeneration (AMD), a leading cause of vision loss. The goal is to see if a single injection into the eye can reduce the need for regular anti-VEGF injections. About 215 adults aged 50 and older who currently need ongoing eye injections will participate.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Austin Clinical Research
RECRUITINGAustin, Texas, 78750, United States
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Barnet Delaney Perkins Eye Center
RECRUITINGPhoenix, Arizona, 85016, United States
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California Retina Consultants
RECRUITINGOxnard, California, 93036, United States
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Colorado Retina Associates
RECRUITINGLakewood, Colorado, 80288, United States
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Cumberland Valley Retina Consultants
RECRUITINGHagerstown, Maryland, 21740, United States
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Contact Email: •••••@•••••
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Emanuelli Research and Development Center, LLC
RECRUITINGArecibo, Puerto Rico, 00612, Puerto Rico
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Contact Email: •••••@•••••
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Florida Eye Associates
RECRUITINGMelbourne, Florida, 32901, United States
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Mid Atlantic Retina
RECRUITINGBethlehem, Pennsylvania, 18017, United States
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Ophthalmic Consultants of Boston & Boston Eye Surgery and Laser Center
RECRUITINGBoston, Massachusetts, 02114, United States
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Contact Email: •••••@•••••
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Pacific Northwest Retina LLC
WITHDRAWNBellevue, Washington, 98004, United States
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Palmetto Retina Center, LLC
RECRUITINGWest Columbia, South Carolina, 29169, United States
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Rand Eye Institute
SUSPENDEDDeerfield Beach, Florida, 33064, United States
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Retina Consultants of Texas
WITHDRAWNThe Woodlands, Texas, 77384, United States
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Retina Partners Midwest
RECRUITINGCarmel, Indiana, 46290, United States
Contact Email: •••••@•••••
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Retina Vitreous Associates of Florida
RECRUITINGTampa, Florida, 33607, United States
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Contact Email: •••••@•••••
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Retina Vitreous Consultants, LLP DBA Retina Group of Florida
ACTIVE_NOT_RECRUITINGFort Lauderdale, Florida, 33308, United States
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Retinal Consultants Medical Group
RECRUITINGSacramento, California, 95841, United States
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Retinal Specialty Institute
RECRUITINGPensacola, Florida, 32503, United States
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Contact Email: •••••@•••••
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Sierra Eye Associates
RECRUITINGReno, Nevada, 89502, United States
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Tennessee Retina
RECRUITINGNashville, Tennessee, 37203, United States
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Contact Email: •••••@•••••
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University Retina and Macula Associates
RECRUITINGOak Forest, Illinois, 60452, United States
Contact Email: •••••@•••••
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Valley Retina Institute, PA
RECRUITINGMcAllen, Texas, 78503, United States
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Contact Email: •••••@•••••
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Verum Research, LLC
RECRUITINGEugene, Oregon, 97401, United States
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Contact Email: •••••@•••••
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Vitreo Retinal Associates
RECRUITINGGainesville, Florida, 32607, United States
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Contact Email: •••••@•••••
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Western Carolina Retinal Associates
WITHDRAWNAsheville, North Carolina, 28803, United States
Conditions
Explore the condition pages connected to this study.