One shot could replace monthly eye injections for vision loss

NCT ID NCT04514653

Summary

This study is testing a one-time gene therapy injection for wet age-related macular degeneration (wet AMD), a leading cause of vision loss in older adults. The goal is to see if this single treatment can work as well as or better than the current standard of care, which requires monthly eye injections. Researchers will compare the gene therapy against the approved drug ranibizumab in about 146 participants over 52 to 80 weeks.

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Contacts and locations

Locations

  • California Retina Consultants - Bakersfield /ID# 255910

    Bakersfield, California, 93309-1677, United States

  • California Retina Consultants - Santa Barbara /ID# 255923

    Santa Barbara, California, 93103, United States

  • Charles Retina Institute /ID# 255922

    Germantown, Tennessee, 38138, United States

  • Duke University Medical Center /ID# 267646

    Durham, North Carolina, 27710, United States

  • Eye Associates of New Mexico /ID# 255915

    Albuquerque, New Mexico, 87109, United States

  • Johns Hopkins Hospital /ID# 255919

    Baltimore, Maryland, 21287, United States

  • Mid Atlantic Retina /ID# 255906

    Philadelphia, Pennsylvania, 19107, United States

  • Northern California Retina Vitreous Associates Medical Group, Inc /ID# 255920

    Mountain View, California, 94040-4101, United States

  • Ophthalmic Consultants of Boston /ID# 255917

    Boston, Massachusetts, 02114, United States

  • Retina Consultants - The Woodlands /ID# 255924

    The Woodlands, Texas, 77384, United States

  • Retina Consultants of San Diego /ID# 255911

    Poway, California, 92064-2530, United States

  • Retina Vitreous Assoc Med Grp /ID# 255921

    Beverly Hills, California, 90211, United States

  • Retinal Diagnostic Center /ID# 272275

    Campbell, California, 95008, United States

  • Retinal Research Institute /ID# 255925

    Phoenix, Arizona, 85053, United States

  • Sierra Eye Associates /ID# 255908

    Reno, Nevada, 89502, United States

  • Southeast Retina Center /ID# 255912

    Augusta, Georgia, 30909, United States

  • Springfield Clinic - First /ID# 272274

    Springfield, Illinois, 62702, United States

  • Tennessee Retina - Nashville /ID# 255918

    Nashville, Tennessee, 37203-1513, United States

Conditions

Explore the condition pages connected to this study.