Gene-Fixed skin grafts offer hope for rare blistering disease
NCT ID NCT04186650
First seen Feb 12, 2026 · Last updated Jun 14, 2026 · Updated 19 times
Summary
This early-stage trial tests a one-time treatment for recessive dystrophic epidermolysis bullosa (RDEB), a rare genetic condition causing fragile, blistering skin. Doctors take a small piece of the patient's skin, fix the faulty gene in a lab, grow it into a healthy sheet, and graft it back onto damaged areas up to 300 cm². The study involves 3 adults and primarily checks for safety, while also looking for improved skin strength and healing.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Institut Imagine Necker Hospital
Paris, 75743, France
Conditions
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