One-Shot gene therapy could slash bleeding in hemophilia a
NCT ID NCT06833983
First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 32 times
Summary
This study tests a single-dose gene therapy called GS1191-0445 for adults with hemophilia A, a bleeding disorder. The therapy uses a harmless virus to deliver a working gene to the liver, helping the body produce its own clotting factor. Researchers will measure how well it reduces bleeding episodes and check for side effects over 52 weeks. The trial enrolls 50 Chinese men aged 18 to 65 who have used factor VIII products before.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Anhui Provincial Hospital
NOT_YET_RECRUITINGHefei, Anhui, 230001, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Central Hospital Affiliated to Shandong First Medical University
RECRUITINGJinan, Shandong, 250013, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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First Hospital of Lanzhou University
NOT_YET_RECRUITINGLanzhou, Gansu, 730099, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Henan Cancer Hospital
NOT_YET_RECRUITINGZhengzhou, Henan, 450003, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Institute of Hematology & Blood Diseases Hospital Chinese Academy of Medical Sciences & Peking Union Medical College
RECRUITINGTianjin, Tianjin Municipality, 300020, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Jiangxi Provincial People's Hospital
NOT_YET_RECRUITINGNanchang, Jiangxi, 344001, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Nanfang Hospital Southern Medical University
NOT_YET_RECRUITINGGuangzhou, Guangdong, 510515, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School
NOT_YET_RECRUITINGNanjing, Jiangsu, 210000, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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North China University of Science and Technology Affiliated Hospital
NOT_YET_RECRUITINGTangshan, Hebei, 063000, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Peking Union Medical College Hospital
NOT_YET_RECRUITINGBeijing, Beijing Municipality, 100005, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The second Affiliated Hospital of Kunming Medical University
NOT_YET_RECRUITINGKunming, Yunnan, 650101, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
NOT_YET_RECRUITINGWuhan, Hubei, 430022, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Xiangya Hospital of Central South University
NOT_YET_RECRUITINGChangsha, Hunan, 410028, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
Explore the condition pages connected to this study.