One-Shot gene therapy aims to control bleeding in hemophilia a

NCT ID NCT06111638

First seen Mar 22, 2026 · Last updated Apr 24, 2026 · Updated 2 times

Summary

This study tests a one-time gene therapy injection (BBM-H803) for adults with severe hemophilia A. The treatment uses a harmless virus to deliver a working gene so the body can make its own clotting factor VIII. The goal is to reduce or prevent bleeding episodes. The trial is currently recruiting 55 participants.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Affiliated Hospital of Guizhou Medical University

    RECRUITING

    Guiyang, Guizhou, 550001, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Institute of Hematology & Blood Diseases Hospital Chinese Academy of Medical Sciences & Peking Union Medical College

    RECRUITING

    Tianjin, Tianjin Municipality, 300020, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Peking Union Medical College Hospital, Chinese Academy of Medical Sciences

    RECRUITING

    Beijing, Beijing Municipality, 100005, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Sichuan Provincial People's Hospital

    RECRUITING

    Chengde, Sichuan, 610031, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Southern Hospital, Southern Medical University

    RECRUITING

    Guangzhou, Guangdong, 510515, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Affiliated Hospital of Northwest University Xi'an No.3 Hospital

    RECRUITING

    Xi’an, Shanxi, 710000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Affiliated Hospital of Soochow University

    RECRUITING

    Suzhou, Jiangsu, 215006, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Second Affiliated Hospital of Kunming Medical University

    RECRUITING

    Kunming, Yunnan, 650032, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Wuhan Union Hospital Affiliated to Huazhong University of Science and Technology

    RECRUITING

    Wuhan, Hubei, 430000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Xiangya Hospital Central South University

    RECRUITING

    Changsha, Hunan, 410008, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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