Gene therapy trial aims to tame severe seizures in kids with dravet syndrome

NCT ID NCT06283212

First seen Jan 05, 2026 · Last updated May 14, 2026 · Updated 17 times

Summary

This study tests a gene therapy called ETX101 in 5 children aged 6 months to under 4 years with Dravet syndrome, a severe epilepsy. The treatment uses a harmless virus to deliver a working gene to brain cells, aiming to reduce seizures and improve development. The main goals are to check safety and see if seizures and daily living skills get better over a year.

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Contacts and locations

Locations

  • Great Ormond Street Hospital

    London, WC1N3JH, United Kingdom

  • Queen Elizabeth Hospital

    Glasgow, G51 4TF, United Kingdom

  • Sheffield Children's Hospital

    Sheffield, S10 2TH, United Kingdom

Conditions

Explore the condition pages connected to this study.