Could a gene test predict your best asthma treatment?

NCT ID NCT03694158

Summary

This study aims to see if people with a specific gene variant (IL-4RαR576) respond better to the asthma drug dupilumab. About 150 participants, ages 12 and older with moderate-to-severe asthma, will receive either the drug or a placebo for 48 weeks. The main goal is to see if the drug reduces the rate of serious asthma attacks, especially for those with the gene variant.

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Contacts and locations

Locations

  • Boston Children's Hospital

    Boston, Massachusetts, 02115, United States

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States

  • Henry Ford Health System

    Detroit, Michigan, 48202, United States

  • MetroHealth System

    Cleveland, Ohio, 44109, United States

  • Montefiore Einstein Clinical Research Center

    The Bronx, New York, 10467, United States

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

Conditions

Explore the condition pages connected to this study.