Scientists hunt genetic clues in zebrafish to solve rare brain disease mysteries

This research project aims to understand how specific large-scale genetic changes cause rare congenital brain disorders. Researchers will study DNA from up to 10,000 people with suspected rare diseases to pinpoint these changes and then test their effects using patient cells and zebrafish models. The goal is to improve genetic diagnosis and lay the groundwork for future treatments, but this study itself does not provide direct treatment to participants.