Lung cancer study maps genetic resistance to key drug

NCT ID NCT05219162

First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 32 times

Summary

This study looked at gene changes in 182 people with advanced lung cancer whose first treatment with the drug Osimertinib stopped working. Researchers collected tumor tissue and blood samples to find out why the drug failed and what other treatments might work next. The goal is to help doctors choose better follow-up therapies based on each person's unique gene profile.

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Contacts and locations

Locations

  • Research Site

    Beijing, 100210, China

  • Research Site

    Changsha, 410013, China

  • Research Site

    Chengdu, 610014, China

  • Research Site

    Dalian, 116023, China

  • Research Site

    Foshan, 528000, China

  • Research Site

    Fuzhou, 350014, China

  • Research Site

    Harbin, 150081, China

  • Research Site

    Hefei, 230001, China

  • Research Site

    Hefei, 230601, China

  • Research Site

    Linhai, 317000, China

  • Research Site

    Luoyang, 471003, China

  • Research Site

    Rizhao, 276826, China

  • Research Site

    Shanghai, 200032, China

  • Research Site

    Taizhou, 225300, China

  • Research Site

    Tianjin, 300060, China

  • Research Site

    Zhengzhou, 450000, China

Conditions

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