Scientists probe gene link to MS Drug's side effects

NCT ID NCT04410965

Summary

This study aimed to understand if a specific gene mutation (ABCG2) affects how much of the multiple sclerosis drug teriflunomide stays in a patient's body and its safety. It involved 82 Chinese patients with relapsing multiple sclerosis who took the standard 14 mg dose daily for 24 weeks. Researchers compared patients with and without the gene mutation to see if it influenced drug levels or side effects like liver issues or hair thinning.

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Contacts and locations

Locations

  • Investigational Site Number

    China, China

Conditions

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