DNA test could make chemo safer for kids with leukemia

NCT ID NCT07462299

First seen Mar 10, 2026 · Last updated May 16, 2026 · Updated 11 times

Summary

This study aims to see if using a child's genetic information to decide the dose of a chemotherapy drug (6-MP) can lower the risk of dangerous low white blood cell counts and infections. About 110 children with acute lymphoblastic leukemia will receive a personalized dose based on their NUDT15 and TPMT genes. The goal is to make maintenance therapy safer while still controlling the disease.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The Children's Hospital of Zhejiang University School of Medicine

    Hangzhou, Zhejiang, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.