Triple therapy shows promise against tough bile duct cancer

NCT ID NCT05668884

First seen Jan 26, 2026 · Last updated Apr 24, 2026 · Updated 10 times

Summary

This study tests a new combination of three drugs—chemotherapy (GEMOX), a targeted therapy (Donafenib), and an immunotherapy (Tislelizumab)—in people with advanced biliary tract cancer that cannot be removed by surgery. The goal is to see if this mix shrinks tumors and improves survival. About 93 adults aged 18–75 with stage III/IV disease will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Fudan University Shanghai Cancer Center

    RECRUITING

    Shanghai, Shanghai Municipality, 200062, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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