Engineered immune cells take on Hard-to-Treat tumors in early trial
NCT ID NCT07297667
First seen Jan 11, 2026 · Last updated Apr 24, 2026 · Updated 16 times
Summary
This early-phase study tests a new treatment called GCAR1, which uses a patient's own immune cells (T-cells) that are modified in a lab to recognize and attack cancer cells that have a specific marker (GPNMB). The study enrolls up to 30 people in Canada with advanced sarcoma, kidney cancer, or triple-negative breast cancer that has not responded to other treatments. The main goals are to find a safe dose and see if the therapy can shrink tumors.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Arthur J.E. Child Comprehensive Cancer Centre
Calgary, Alberta, T2N 5G2, Canada
Contact Phone: •••-•••-••••
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Ottawa Hospital Research Institute
Ottawa, Ontario, K1H 8L6, Canada
Contact Phone: •••-•••-••••
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University Health Network Princess Margaret Hospital
Toronto, Ontario, M5G 2M9, Canada
Contact Phone: •••-•••-••••
Conditions
Explore the condition pages connected to this study.