Supercharged immune cells take on tough gynecologic cancers

NCT ID NCT05468307

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early study tested a new therapy called GC203 TIL in 26 people with advanced gynecologic tumors that had stopped responding to standard treatments. Doctors took immune cells from each patient's tumor, genetically modified them to be more powerful, and infused them back. The main goals were to check safety and see if the treatment could shrink tumors or slow disease progression.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

engineered immune cells (GC203 TIL)

What this could lead to

If it works, this could point toward a new treatment option for advanced gynecologic tumors that have not responded to standard therapies.

What could go wrong

This is a very early, small study (26 people) focused on safety. The treatment may not shrink tumors or could cause serious side effects. Results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

female reproductive organ cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Shanghai Tenth People's Hospital

    Shanghai, Shanghai Municipality, 200000, China