New eye drug GB10 enters early human testing for wet AMD

NCT ID NCT07406438

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage trial tests a new drug called GB10, given as an eye injection, for people with wet age-related macular degeneration (AMD). The study will include 48 participants and aims to check safety and find the right dose. It is not yet recruiting and is too early to know if the drug works.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

GB10 (intravitreal injection)

What this could lead to

If successful, this could point toward a new treatment option for wet age-related macular degeneration that may reduce the need for frequent eye injections.

What could go wrong

This is a very early Phase 1 trial with only 48 participants, focused on safety and dosing. It is too small and early to know if GB10 will work or be safe long-term.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

wet macular degeneration

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Beijing Tongren Hospital, Capital Medical University

    Beijing, Beijing Municipality, 100730, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

  • Henan Provincial Eye Hospital

    Zhengzhou, Henan, 450015, China

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Nanchang University Second Affiliated Hospital

    Nanchang, Jiangxi, 330006, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Sir Run Run Shaw Hospital (SRRSH), affiliated with Zhejiang University School of Medicine

    Hangzhou, Zhejiang, 310016, China

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Affiliated Hospital of Guizhou Medical University

    Guiyang, Guizhou, 550004, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Zhejiang Provincial People's Hospital

    Hangzhou, Zhejiang, 310014, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact