Vitamin c shown to briefly change stomach acidity in small study
NCT ID NCT04199624
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This completed Phase 1 study tested whether vitamin C (ascorbic acid) tablets can temporarily reduce stomach pH (increase acidity) in 11 healthy young men whose stomach acid was lowered by the drug omeprazole. Participants took vitamin C once and had their stomach pH monitored for five hours. The study also looked at how stomach pH changes might relate to gut bacteria and metabolites.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Vitamin C (ascorbic acid)
What this could lead to
If successful, this could point toward a simple way to temporarily adjust stomach acidity for certain medical situations.
What could go wrong
This is a very small, early-phase study in healthy young men only, so results may not apply to patients or real-world conditions.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for HYPOCHLORHYDRIA are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Indiana University School of Medicine
Indianapolis, Indiana, 46202, United States