New combo shows promise in shrinking stomach tumors before surgery

NCT ID NCT04736485

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether adding the immunotherapy drug spartalizumab to standard chemotherapy (FLOT) helps shrink stomach cancer before surgery and prevent it from coming back. 67 adults with resectable stomach or gastroesophageal junction cancer received the combination before and after surgery. The main goal was to see how many patients had no cancer cells left in their tumor after the pre-surgery treatment.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • APHM Marseille

    Marseille, France

  • APHP St Louis

    Paris, France

  • CH St Malo

    St-Malo, France

  • CHU Besançon

    Besançon, France

  • CHU Poitiers

    Poitiers, France

  • CHU Robert Debré

    Reims, France

  • Centre Eugène Marquis

    Rennes, France

  • Centre François Baclesse

    Caen, France

  • Centre Georges Francois Leclerc

    Dijon, France

  • Chru Lille

    Lille, France

  • ICO St Herblain

    Saint-Herblain, France

  • Institut Mutualiste Montsouris

    Paris, France

  • Institut Régional Cancer

    Montpellier, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.