Can an antiviral drug help sepsis patients breathe easier?
NCT ID NCT04706507
First seen Jan 11, 2026 · Last updated May 01, 2026 · Updated 15 times
Summary
This study tested whether the antiviral drug ganciclovir could prevent the reactivation of cytomegalovirus (CMV) in adults with sepsis and acute respiratory failure. The goal was to see if it would increase the number of days patients could breathe without a ventilator. The study included 205 participants in the ICU who had CMV antibodies. The trial was terminated early, so results are limited.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Brigham & Women's Hospital
Boston, Massachusetts, 02115, United States
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Duke University
Durham, North Carolina, 27708, United States
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Harborview Medical Center
Seattle, Washington, 98104, United States
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Henry Ford Hospital
Detroit, Michigan, 48202, United States
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Intermountain Medical Center
Murray, Utah, 84107, United States
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Johns Hopkins University
Baltimore, Maryland, 21218, United States
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Medical College of South Carolina
Charleston, South Carolina, 29425, United States
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Montefioure Medical Center
The Bronx, New York, 10467, United States
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Ohio State University Medical Center
Columbus, Ohio, 43210, United States
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The Cleveland Clinic Foundation
Cleveland, Ohio, 44195, United States
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University of Cincinnati
Cincinnati, Ohio, 45221, United States
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University of Colorado Denver
Denver, Colorado, 80204, United States
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University of Michigan
Ann Arbor, Michigan, 48109-5360, United States
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University of Pittsburgh Medical Center
Pittsburgh, Pennsylvania, 15261, United States
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University of Vermont College of Medicine
Burlington, Vermont, 05405, United States
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University of Washington Medical Center
Seattle, Washington, 98195, United States
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University of Wisconsin School of Medicine & Public Health
Madison, Wisconsin, 53792, United States
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Vanderbilt University
Nashville, Tennessee, 37235, United States
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Wakeforest University, School of Medicine
Winston-Salem, North Carolina, 27157, United States
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Washington University
St Louis, Missouri, 63130, United States
Conditions
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