Can a Game-Like app retrain your brain to beat depression?

NCT ID NCT05601362

First seen Jul 06, 2026 · Last updated Jul 07, 2026 · Updated 1 time

Summary

This study tests a gamified mobile app designed to reduce symptoms of depression and rumination (repetitive negative thinking). People with moderate or greater depression use the app for four weeks, completing daily surveys and weekly assessments. The app uses attention bias modification training to gently shift focus away from negative stimuli. The goal is to see if this digital tool can improve mood and thinking patterns.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Gamified Attention Bias Modification (GAMBT) mobile app
What this could lead to
If effective, this app could offer a low-cost, accessible tool to help people with depression reduce symptoms and repetitive negative thinking.
What could go wrong
This is a small, early-stage study with no control for long-term effects. The intervention may not outperform the placebo version, and results may not generalize to all people with depression.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Mary Eileen McNamara

    Austin, Texas, 78712, United States

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