New strategy aims to boost survival in gallbladder cancer

NCT ID NCT04559139

Ongoing Disease control Sponsor: ECOG-ACRIN Cancer Research Group Source: ClinicalTrials.gov ↗

Summary

This study is testing whether giving chemotherapy both before and after surgery works better than giving it only after surgery for people with stage II or III gallbladder cancer. About 186 patients will be randomly assigned to receive the standard treatment (surgery followed by chemo) or the new approach (chemo, then surgery, then more chemo). The main goal is to see if the new approach helps patients live longer and keeps the cancer from coming back.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Alaska Breast Care and Surgery LLC

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Alaska Oncology and Hematology LLC

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Alaska Women's Cancer Care

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Albany Medical Center

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Anchorage Associates in Radiation Medicine

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Atrium Medical Center-Middletown Regional Hospital

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Springfield, Missouri, 65807, United States
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Troy, Ohio, 45373, United States
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Centerville, Ohio, 45459, United States
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Delbert Day Cancer Institute at PCRMC

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Bremerton, Washington, 98310, United States
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Poulsbo, Washington, 98370, United States
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Princeton, Illinois, 61356, United States
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Legacy Cancer Institute Medical Oncology and Day Treatment

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Vancouver, Washington, 98686, United States
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Lovelace Medical Center-Saint Joseph Square

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Low Country Cancer Care

Savannah, Georgia, 31404, United States
Lowell General Hospital

Lowell, Massachusetts, 01854, United States
MU Health Care Goldschmidt Cancer Center

Jefferson City, Missouri, 65109, United States
Marshfield Clinic-Minocqua Center

Minocqua, Wisconsin, 54548, United States
Marshfield Medical Center - Weston

Weston, Wisconsin, 54476, United States
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Eau Claire, Wisconsin, 54701, United States
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Rochester, Minnesota, 55905, United States
Medical University of South Carolina

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Savannah, Georgia, 31404, United States
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Carbondale, Illinois, 62902, United States
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Springfield, Illinois, 62781, United States
Memorial Sloan Kettering Basking Ridge

Basking Ridge, New Jersey, 07920, United States
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Montvale, New Jersey, 07645, United States
Memorial Sloan Kettering Cancer Center

New York, New York, 10065, United States
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Commack, New York, 11725, United States
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Middletown, New Jersey, 07748, United States
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Uniondale, New York, 11553, United States
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East White Plains, New York, 10604, United States
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Clive, Iowa, 50325, United States
Mercy Clinic-Rolla-Cancer and Hematology

Rolla, Missouri, 65401, United States
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Fort Smith, Arkansas, 72903, United States
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Oklahoma City, Oklahoma, 73120, United States
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Des Moines, Iowa, 50314, United States
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West Des Moines, Iowa, 50266, United States
Mercy San Juan Medical Center

Carmichael, California, 95608, United States
Methodist Medical Center of Illinois

Peoria, Illinois, 61636, United States
Methodist West Hospital

West Des Moines, Iowa, 50266-7700, United States
MetroHealth Medical Center

Cleveland, Ohio, 44109, United States
Miami Valley Cancer Care and Infusion

Greenville, Ohio, 45331, United States
Miami Valley Hospital

Dayton, Ohio, 45409, United States
Miami Valley Hospital North

Dayton, Ohio, 45415, United States
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Centerville, Ohio, 45459, United States
Midlands Community Hospital

Papillion, Nebraska, 68046, United States
Mission Cancer and Blood - Ankeny

Ankeny, Iowa, 50023, United States
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Des Moines, Iowa, 50309, United States
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Des Moines, Iowa, 50314, United States
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Clive, Iowa, 50325, United States
Mission Hope Medical Oncology - Arroyo Grande

Arroyo Grande, California, 93420, United States
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Santa Maria, California, 93444, United States
Missouri Baptist Medical Center

St Louis, Missouri, 63131, United States
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Sullivan, Missouri, 63080, United States
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Long Branch, New Jersey, 07740, United States
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Lakewood, New Jersey, 08701, United States
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Traverse City, Michigan, 49684, United States
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Jonesboro, Arkansas, 72401, United States
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Nebraska Cancer Specialists/Oncology Hematology West PC

Grand Island, Nebraska, 68803, United States
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Newark, New Jersey, 07112, United States
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Manhasset, New York, 11030, United States
Northeast Georgia Medical Center Braselton

Braselton, Georgia, 30517, United States
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Gainesville, Georgia, 30501, United States
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Warrenville, Illinois, 60555, United States
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Chicago, Illinois, 60611, United States
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Peoria, Illinois, 61637, United States
OSF Saint Francis Radiation Oncology at Pekin

Pekin, Illinois, 61554, United States
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Peoria, Illinois, 61615, United States
Ohio State University Comprehensive Cancer Center

Columbus, Ohio, 43210, United States
Oncology Hematology Care Inc-Kenwood

Cincinnati, Ohio, 45236, United States
Oregon Health and Science University

Portland, Oregon, 97239, United States
Orion Cancer Care

Findlay, Ohio, 45840, United States
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San Luis Obispo, California, 93401, United States
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Seattle, Washington, 98104, United States
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Parker, Colorado, 80138, United States
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Farmington, Missouri, 63640, United States
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Dallas, Texas, 75235, United States
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Bellingham, Washington, 98225, United States
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Vancouver, Washington, 98664, United States
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Sedro-Woolley, Washington, 98284, United States
Penn State Milton S Hershey Medical Center

Hershey, Pennsylvania, 17033-0850, United States
Penrose-Saint Francis Healthcare

Colorado Springs, Colorado, 80907, United States
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Denver, Colorado, 80210, United States
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Dayton, Ohio, 45409, United States
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Albuquerque, New Mexico, 87110, United States
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Rio Rancho, New Mexico, 87124, United States
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Anchorage, Alaska, 99508, United States
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Clackamas, Oregon, 97015, United States
Providence Medical Foundation - Santa Rosa

Santa Rosa, California, 95403, United States
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Newberg, Oregon, 97132, United States
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Portland, Oregon, 97213, United States
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Napa, California, 94558, United States
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Everett, Washington, 98201, United States
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Aberdeen, Washington, 98520, United States
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Centralia, Washington, 98531, United States
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Lacey, Washington, 98503, United States
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Shelton, Washington, 98584, United States
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Yelm, Washington, 98597, United States
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Burbank, California, 91505, United States
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Portland, Oregon, 97225, United States
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Santa Rosa, California, 95405, United States
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Oregon City, Oregon, 97045, United States
Queens Cancer Center

Rego Park, New York, 11374, United States
Regional Cancer Center-Lee Memorial Health System

Fort Myers, Florida, 33905, United States
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Richmond, Indiana, 47374, United States
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Somerville, New Jersey, 08876, United States
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Longmont, Colorado, 80501, United States
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Charleston, South Carolina, 29401, United States
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Aurora, Illinois, 60504, United States
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Yorkville, Illinois, 60560, United States
Rutgers Cancer Institute of New Jersey

New Brunswick, New Jersey, 08903, United States
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Newark, New Jersey, 07101, United States
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Carterville, Illinois, 62918, United States
Saint Anthony Hospital

Lakewood, Colorado, 80228, United States
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Carroll, Iowa, 51401, United States
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Alton, Illinois, 62002, United States
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Livingston, New Jersey, 07039, United States
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Bend, Oregon, 97701, United States
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Redmond, Oregon, 97756, United States
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Lakewood, Washington, 98499, United States
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Boardman, Ohio, 44512, United States
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Enumclaw, Washington, 98022, United States
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Lincoln, Nebraska, 68510, United States
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Youngstown, Ohio, 44501, United States
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Colorado Springs, Colorado, 80923, United States
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Federal Way, Washington, 98003, United States
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Cape Girardeau, Missouri, 63703, United States
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Lexington, Kentucky, 40504, United States
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Lexington, Kentucky, 40509, United States
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London, Kentucky, 40741, United States
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Mount Sterling, Kentucky, 40353, United States
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Lexington, Kentucky, 40504, United States
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Bryan, Texas, 77802, United States
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Warren, Ohio, 44484, United States
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Ballwin, Missouri, 63011, United States
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Boise, Idaho, 83712, United States
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Fruitland, Idaho, 83619, United States
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Meridian, Idaho, 83642, United States
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Nampa, Idaho, 83686, United States
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Twin Falls, Idaho, 83301, United States
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Pueblo, Colorado, 81004, United States
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Centralia, Illinois, 62801, United States
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Silverdale, Washington, 98383, United States
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Missoula, Montana, 59802, United States
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Sainte Genevieve, Missouri, 63670, United States
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Louisville, Kentucky, 40215, United States
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Bismarck, North Dakota, 58501, United States
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Fargo, North Dakota, 58122, United States
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Sioux Falls, South Dakota, 57104, United States
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Worthington, Minnesota, 56187, United States
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Bemidji, Minnesota, 56601, United States
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Fargo, North Dakota, 58104, United States
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Fargo, North Dakota, 58122, United States
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Fargo, North Dakota, 58103, United States
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Thief River Falls, Minnesota, 56701, United States
Sanford USD Medical Center - Sioux Falls

Sioux Falls, South Dakota, 57117-5134, United States
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St Louis, Missouri, 63136, United States
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City of Saint Peters, Missouri, 63376, United States
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Creve Coeur, Missouri, 63141, United States
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St Louis, Missouri, 63129, United States
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Cape Girardeau, Missouri, 63703, United States
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Springfield, Illinois, 62702, United States
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Fargo, North Dakota, 58103, United States
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Durango, Colorado, 81301, United States
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Springfield, Illinois, 62702, United States
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Springfield, Ohio, 45504, United States
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Springfield, Ohio, 45504, United States
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Palo Alto, California, 94304, United States
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Stony Brook, New York, 11794, United States
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Savannah, Georgia, 31404, United States
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Edmonds, Washington, 98026, United States
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Issaquah, Washington, 98029, United States
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Seattle, Washington, 98107, United States
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Seattle, Washington, 98122-5711, United States
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Seattle, Washington, 98122, United States
The Cancer Institute of New Jersey Hamilton

Hamilton, New Jersey, 08690, United States
The James Graham Brown Cancer Center at University of Louisville

Louisville, Kentucky, 40202, United States
Thomas Jefferson University Hospital

Philadelphia, Pennsylvania, 19107, United States
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Torrance, California, 90509, United States
Torrance Memorial Physician Network - Cancer Care

Torrance, California, 90505, United States
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Cincinnati, Ohio, 45255, United States
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Cincinnati, Ohio, 45247, United States
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Elizabeth, New Jersey, 07207, United States
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Grand Rapids, Michigan, 49503, United States
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Muskegon, Michigan, 49444, United States
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Fort Dodge, Iowa, 50501, United States
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New Lenox, Illinois, 60451, United States
UC Irvine Health/Chao Family Comprehensive Cancer Center

Orange, California, 92868, United States
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Aventura, Florida, 33180, United States
UM Sylvester Comprehensive Cancer Center at Coral Gables

Coral Gables, Florida, 33146, United States
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Deerfield Beach, Florida, 33442, United States
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Miami, Florida, 33176, United States
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Plantation, Florida, 33324, United States
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Worcester, Massachusetts, 01655, United States
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Richardson, Texas, 75080, United States
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Dallas, Texas, 75390, United States
United Hospital Center

Bridgeport, West Virginia, 26330, United States
University of Alabama at Birmingham Cancer Center

Birmingham, Alabama, 35233, United States
University of Arkansas for Medical Sciences

Little Rock, Arkansas, 72205, United States
University of California Davis Comprehensive Cancer Center

Sacramento, California, 95817, United States
University of Chicago Comprehensive Cancer Center

Chicago, Illinois, 60637, United States
University of Chicago Medicine-Orland Park

Orland Park, Illinois, 60462, United States
University of Florida Health Science Center - Gainesville

Gainesville, Florida, 32610, United States
University of Illinois

Chicago, Illinois, 60612, United States
University of Kentucky/Markey Cancer Center

Lexington, Kentucky, 40536, United States
University of Miami Miller School of Medicine-Sylvester Cancer Center

Miami, Florida, 33136, United States
University of Michigan - Brighton Center for Specialty Care

Brighton, Michigan, 48116, United States
University of Michigan Comprehensive Cancer Center

Ann Arbor, Michigan, 48109, United States
University of Michigan Health - West

Wyoming, Michigan, 49519, United States
University of New Mexico Cancer Center

Albuquerque, New Mexico, 87106, United States
University of Pennsylvania/Abramson Cancer Center

Philadelphia, Pennsylvania, 19104, United States
University of Rochester

Rochester, New York, 14642, United States
University of Tennessee - Knoxville

Knoxville, Tennessee, 37920, United States
University of Texas Health Science Center at San Antonio

San Antonio, Texas, 78229, United States
University of Wisconsin Carbone Cancer Center - University Hospital

Madison, Wisconsin, 53792, United States
UofL Health Medical Center Northeast

Louisville, Kentucky, 40245, United States
Upper Valley Medical Center

Troy, Ohio, 45373, United States
Valley Radiation Oncology

Peru, Illinois, 61354, United States
Vanderbilt Breast Center at One Hundred Oaks

Nashville, Tennessee, 37204, United States
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Nashville, Tennessee, 37232, United States
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Franklin, Tennessee, 37067, United States
Vanderbilt-Ingram Cancer Center at Franklin

Franklin, Tennessee, 37067, United States
Virginia Mason Medical Center

Seattle, Washington, 98101, United States
WVUH-Berkely Medical Center

Martinsburg, West Virginia, 25401, United States
Wake Forest University Health Sciences

Winston-Salem, North Carolina, 27157, United States
Washington University School of Medicine

St Louis, Missouri, 63110, United States
Wayne Hospital

Greenville, Ohio, 45331, United States
West Michigan Cancer Center

Kalamazoo, Michigan, 49007, United States
West Virginia University Healthcare

Morgantown, West Virginia, 26506, United States
Western Illinois Cancer Treatment Center

Galesburg, Illinois, 61401, United States
Woodland Memorial Hospital

Woodland, California, 95695, United States

Conditions

Explore the condition pages connected to this study.

STAGE II GALLBLADDER CANCER AJCC V8 STAGE IIA GALLBLADDER CANCER AJCC V8 STAGE IIB GALLBLADDER CANCER AJCC V8 STAGE III GALLBLADDER CANCER AJCC V8 STAGE IIIA GALLBLADDER CANCER AJCC V8 STAGE IIIB GALLBLADDER CANCER AJCC V8