New hope to spare cancer patients from opioid addiction during treatment

NCT ID NCT06992427

Recruiting now Symptom relief Sponsor: Alliance for Clinical Trials in Oncology Source: ClinicalTrials.gov ↗

Summary

This large, late-stage trial is testing if a high dose of the drug gabapentin, started early, can prevent the need for strong opioid painkillers in patients receiving chemotherapy and radiation for head and neck cancer. The goal is to manage the severe mouth sores and pain that are common side effects of treatment, while avoiding the side effects and addiction risks of opioids. Researchers will compare gabapentin to a placebo in about 228 patients to see which group needs fewer opioids and reports less pain.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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AIS Cancer Center at San Joaquin Community Hospital
RECRUITING

Bakersfield, California, 93301, United States

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Allegheny General Hospital
RECRUITING

Pittsburgh, Pennsylvania, 15212, United States

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Arizona Center for Cancer Care
RECRUITING

Tempe, Arizona, 85284, United States

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Arizona Center for Cancer Care - Biltmore
RECRUITING

Phoenix, Arizona, 85016, United States

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Arizona Center for Cancer Care - Gilbert
RECRUITING

Gilbert, Arizona, 85297, United States

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Arizona Center for Cancer Care - Osborn
RECRUITING

Scottsdale, Arizona, 85251, United States

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Arizona Center for Cancer Care - Phoenix
RECRUITING

Phoenix, Arizona, 85027, United States

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Arizona Center for Cancer Care - Scottsdale
RECRUITING

Scottsdale, Arizona, 85258, United States

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Arizona Center for Cancer Care-Peoria
RECRUITING

Peoria, Arizona, 85381, United States

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Arizona Center for Cancer Care-Surprise
RECRUITING

Surprise, Arizona, 85374, United States

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Aspirus Cancer Care - James Beck Cancer Center
RECRUITING

Rhinelander, Wisconsin, 54501, United States

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Aspirus Cancer Care - Stevens Point
RECRUITING

Stevens Point, Wisconsin, 54481, United States

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Aspirus Cancer Care - Wisconsin Rapids
RECRUITING

Wisconsin Rapids, Wisconsin, 54494, United States

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Aspirus Medford Hospital
RECRUITING

Medford, Wisconsin, 54451, United States

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Aspirus Regional Cancer Center
RECRUITING

Wausau, Wisconsin, 54401, United States

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Asplundh Cancer Pavilion
RECRUITING

Willow Grove, Pennsylvania, 19090, United States

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Aultman Health Foundation
RECRUITING

Canton, Ohio, 44710, United States

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Benefis Sletten Cancer Institute
RECRUITING

Great Falls, Montana, 59405, United States

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Billings Clinic Cancer Center
RECRUITING

Billings, Montana, 59101, United States

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Bozeman Health Deaconess Hospital
RECRUITING

Bozeman, Montana, 59715, United States

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CHI Health Good Samaritan
SUSPENDED

Kearney, Nebraska, 68847, United States
Camden Clark Medical Center
RECRUITING

Parkersburg, West Virginia, 26101, United States

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Cancer Care Center of O'Fallon
RECRUITING

O'Fallon, Illinois, 62269, United States

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Cancer Care Specialists of Illinois - Decatur
RECRUITING

Decatur, Illinois, 62526, United States

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Carle BroMenn Medical Center
RECRUITING

Normal, Illinois, 61761, United States

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Carle Cancer Center
RECRUITING

Urbana, Illinois, 61801, United States

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Carle Cancer Institute Normal
RECRUITING

Normal, Illinois, 61761, United States

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Carle Physician Group-Effingham
RECRUITING

Effingham, Illinois, 62401, United States

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Carle Physician Group-Mattoon/Charleston
RECRUITING

Mattoon, Illinois, 61938, United States

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Carle at The Riverfront
RECRUITING

Danville, Illinois, 61832, United States

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Coborn Cancer Center at Saint Cloud Hospital
RECRUITING

Saint Cloud, Minnesota, 56303, United States

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Community Hospital of Anaconda
RECRUITING

Anaconda, Montana, 59711, United States

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Community Medical Center
RECRUITING

Missoula, Montana, 59804, United States

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Crossroads Cancer Center
RECRUITING

Effingham, Illinois, 62401, United States

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Decatur Memorial Hospital
RECRUITING

Decatur, Illinois, 62526, United States

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Drexel Town Square Health Center
RECRUITING

Oak Creek, Wisconsin, 53154, United States

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Farmington Health Center
RECRUITING

Farmington, Utah, 84025, United States

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Forbes Hospital
RECRUITING

Monroeville, Pennsylvania, 15146, United States

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Freeman Health System
RECRUITING

Joplin, Missouri, 64804, United States

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Froedtert Menomonee Falls Hospital
RECRUITING

Menomonee Falls, Wisconsin, 53051, United States

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Froedtert West Bend Hospital/Kraemer Cancer Center
RECRUITING

West Bend, Wisconsin, 53095, United States

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Geisinger Cancer Center Dickson City
RECRUITING

Dickson City, Pennsylvania, 18519, United States

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Geisinger Cancer Services-Pottsville
RECRUITING

Pottsville, Pennsylvania, 17901, United States

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Geisinger Medical Center
RECRUITING

Danville, Pennsylvania, 17822, United States

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Geisinger Medical Oncology-Lewisburg
RECRUITING

Lewisburg, Pennsylvania, 17837, United States

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Geisinger Wyoming Valley/Henry Cancer Center
RECRUITING

Wilkes-Barre, Pennsylvania, 18711, United States

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Gundersen Lutheran Medical Center
RECRUITING

La Crosse, Wisconsin, 54601, United States

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HSHS Saint Elizabeth's Hospital
RECRUITING

O'Fallon, Illinois, 62269, United States

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Huntsman Cancer Institute/University of Utah
RECRUITING

Salt Lake City, Utah, 84112, United States

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Illinois CancerCare - Washington
RECRUITING

Washington, Illinois, 61571, United States

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Illinois CancerCare-Bloomington
RECRUITING

Bloomington, Illinois, 61704, United States

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Illinois CancerCare-Canton
RECRUITING

Canton, Illinois, 61520, United States

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Illinois CancerCare-Carthage
RECRUITING

Carthage, Illinois, 62321, United States

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Illinois CancerCare-Dixon
RECRUITING

Dixon, Illinois, 61021, United States

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Illinois CancerCare-Eureka
RECRUITING

Eureka, Illinois, 61530, United States

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Illinois CancerCare-Galesburg
RECRUITING

Galesburg, Illinois, 61401, United States

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Illinois CancerCare-Kewanee Clinic
RECRUITING

Kewanee, Illinois, 61443, United States

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Illinois CancerCare-Macomb
RECRUITING

Macomb, Illinois, 61455, United States

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Illinois CancerCare-Ottawa Clinic
RECRUITING

Ottawa, Illinois, 61350, United States

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Illinois CancerCare-Pekin
RECRUITING

Pekin, Illinois, 61554, United States

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Illinois CancerCare-Peoria
RECRUITING

Peoria, Illinois, 61615, United States

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Illinois CancerCare-Peru
RECRUITING

Peru, Illinois, 61354, United States

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Illinois CancerCare-Princeton
RECRUITING

Princeton, Illinois, 61356, United States

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Jefferson Hospital
RECRUITING

Jefferson Hills, Pennsylvania, 15025, United States

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Jefferson Torresdale Hospital
RECRUITING

Philadelphia, Pennsylvania, 19114, United States

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Kaiser Permanente Downtown Commons
RECRUITING

Sacramento, California, 95814, United States

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Kaiser Permanente Dublin
RECRUITING

Dublin, California, 94568, United States

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Kaiser Permanente Fresno Orchard Plaza
RECRUITING

Fresno, California, 93720, United States

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Kaiser Permanente Medical Center - Santa Clara
RECRUITING

Santa Clara, California, 95051, United States

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Kaiser Permanente Moanalua Medical Center
RECRUITING

Honolulu, Hawaii, 96819, United States

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Kaiser Permanente San Leandro
RECRUITING

San Leandro, California, 94577, United States

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Kaiser Permanente- Modesto MOB II
RECRUITING

Modesto, California, 95356, United States

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Kaiser Permanente-Fremont
RECRUITING

Fremont, California, 94538, United States

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Kaiser Permanente-Modesto
RECRUITING

Modesto, California, 95356, United States

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Kaiser Permanente-Oakland
RECRUITING

Oakland, California, 94611, United States

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Kaiser Permanente-Roseville
RECRUITING

Roseville, California, 95661, United States

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Kaiser Permanente-San Francisco
RECRUITING

San Francisco, California, 94115, United States

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Kaiser Permanente-Santa Rosa
RECRUITING

Santa Rosa, California, 95403, United States

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Kaiser Permanente-Santa Teresa-San Jose
RECRUITING

San Jose, California, 95119, United States

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Kaiser Permanente-South Sacramento
RECRUITING

Sacramento, California, 95823, United States

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Kaiser Permanente-South San Francisco
RECRUITING

South San Francisco, California, 94080, United States

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Kaiser Permanente-Vallejo
RECRUITING

Vallejo, California, 94589, United States

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Kaiser Permanente-Walnut Creek
RECRUITING

Walnut Creek, California, 94596, United States

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Kaiser San Rafael-Gallinas
RECRUITING

San Rafael, California, 94903, United States

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Kootenai Clinic Cancer Services - Post Falls
RECRUITING

Post Falls, Idaho, 83854, United States

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Kootenai Clinic Cancer Services - Sandpoint
RECRUITING

Sandpoint, Idaho, 83864, United States

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Kootenai Health - Coeur d'Alene
RECRUITING

Coeur d'Alene, Idaho, 83814, United States

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Langlade Hospital and Cancer Center
RECRUITING

Antigo, Wisconsin, 54409, United States

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Lenox Hill Hospital
RECRUITING

New York, New York, 10075, United States

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Logan Health Medical Center
RECRUITING

Kalispell, Montana, 59901, United States

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Los Angeles General Medical Center
SUSPENDED

Los Angeles, California, 90033, United States
Manhattan Eye Ear and Throat Hospital
RECRUITING

New York, New York, 10065, United States

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Mary Greeley Medical Center
RECRUITING

Ames, Iowa, 50010, United States

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McFarland Clinic - Ames
RECRUITING

Ames, Iowa, 50010, United States

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McFarland Clinic - Boone
RECRUITING

Boone, Iowa, 50036, United States

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McFarland Clinic - Jefferson
RECRUITING

Jefferson, Iowa, 50129, United States

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McFarland Clinic - Marshalltown
RECRUITING

Marshalltown, Iowa, 50158, United States

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McFarland Clinic - Trinity Cancer Center
RECRUITING

Fort Dodge, Iowa, 50501, United States

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Medical College of Wisconsin
RECRUITING

Milwaukee, Wisconsin, 53226, United States

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Mercy Hospital
RECRUITING

Cedar Rapids, Iowa, 52403, United States

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Mercy Hospital Saint Louis
RECRUITING

St Louis, Missouri, 63141, United States

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Mercy Hospital South
RECRUITING

St Louis, Missouri, 63128, United States

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Methodist Jennie Edmundson Hospital
SUSPENDED

Council Bluffs, Iowa, 51503, United States
Montefiore Medical Center - Moses Campus
RECRUITING

The Bronx, New York, 10467, United States

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Montefiore Medical Center-Einstein Campus
RECRUITING

The Bronx, New York, 10461, United States

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Nebraska Medicine-Bellevue
RECRUITING

Bellevue, Nebraska, 68123, United States

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Nebraska Medicine-Village Pointe
RECRUITING

Omaha, Nebraska, 68118, United States

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Nebraska Methodist Hospital
RECRUITING

Omaha, Nebraska, 68114, United States

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Northwell Health Physicians Partners Radiation Medicine at Queens
RECRUITING

Forest Hills, New York, 11375, United States

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Northwell Health/Center for Advanced Medicine
RECRUITING

Lake Success, New York, 11042, United States

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Oncology Associates at Mercy Medical Center
RECRUITING

Cedar Rapids, Iowa, 52403, United States

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Princeton Community Hospital
RECRUITING

Princeton, West Virginia, 24740, United States

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Queens Cancer Center
RECRUITING

Rego Park, New York, 11374, United States

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Roswell Park Cancer Institute
RECRUITING

Buffalo, New York, 14263, United States

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Rush-Copley Medical Center
RECRUITING

Aurora, Illinois, 60504, United States

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Saint Anthony Hospital
RECRUITING

Lakewood, Colorado, 80228, United States

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Saint Francis Medical Center
RECRUITING

Cape Girardeau, Missouri, 63703, United States

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Saint Luke's Cancer Institute - Boise
RECRUITING

Boise, Idaho, 83712, United States

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Saint Luke's Cancer Institute - Fruitland
RECRUITING

Fruitland, Idaho, 83619, United States

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Saint Luke's Cancer Institute - Meridian
RECRUITING

Meridian, Idaho, 83642, United States

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Saint Luke's Cancer Institute - Nampa
RECRUITING

Nampa, Idaho, 83687, United States

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Saint Luke's Hospital
RECRUITING

Cedar Rapids, Iowa, 52402, United States

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Saint Vincent Hospital
RECRUITING

Erie, Pennsylvania, 16544, United States

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Sanford Bismarck Medical Center
RECRUITING

Bismarck, North Dakota, 58501, United States

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Sanford Broadway Medical Center
RECRUITING

Fargo, North Dakota, 58122, United States

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Sanford Cancer Center Oncology Clinic
RECRUITING

Sioux Falls, South Dakota, 57104, United States

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Sanford Joe Lueken Cancer Center
RECRUITING

Bemidji, Minnesota, 56601, United States

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Sanford Roger Maris Cancer Center
RECRUITING

Fargo, North Dakota, 58122, United States

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Sanford USD Medical Center - Sioux Falls
RECRUITING

Sioux Falls, South Dakota, 57117-5134, United States

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South Jordan Health Center
RECRUITING

South Jordan, Utah, 84009, United States

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Southern Illinois University School of Medicine
RECRUITING

Springfield, Illinois, 62702, United States

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Springfield Clinic
RECRUITING

Springfield, Illinois, 62702, United States

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Springfield Memorial Hospital
RECRUITING

Springfield, Illinois, 62781, United States

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Thomas Jefferson University Hospital
RECRUITING

Philadelphia, Pennsylvania, 19107, United States

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Trinity Medical Center
RECRUITING

Moline, Illinois, 61265, United States

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UPMC Cancer Center - Monroeville
RECRUITING

Monroeville, Pennsylvania, 15146, United States

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UPMC Cancer Center at UPMC Horizon
RECRUITING

Farrell, Pennsylvania, 16121, United States

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UPMC Cancer Center at UPMC Northwest
RECRUITING

Seneca, Pennsylvania, 16346, United States

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UPMC Cancer Centers - Arnold Palmer Pavilion
RECRUITING

Greensburg, Pennsylvania, 15601, United States

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Contact Phone: •••-•••-••••
UPMC Hillman Cancer Center - Monroeville
RECRUITING

Monroeville, Pennsylvania, 15146, United States

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UPMC Hillman Cancer Center Erie
RECRUITING

Erie, Pennsylvania, 16505, United States

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Contact Phone: •••-•••-•••• Email: •••••@•••••
UPMC Hillman Cancer Center at Rocco And Nancy Ortenzio Cancer Pavilion
RECRUITING

Mechanicsburg, Pennsylvania, 17050, United States

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UPMC Pinnacle Cancer Center/Community Osteopathic Campus
RECRUITING

Harrisburg, Pennsylvania, 17109, United States

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UPMC-Saint Clair Hospital Cancer Center
RECRUITING

Pittsburgh, Pennsylvania, 15243, United States

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UPMC-Shadyside Hospital
RECRUITING

Pittsburgh, Pennsylvania, 15232, United States

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USC / Norris Comprehensive Cancer Center
SUSPENDED

Los Angeles, California, 90033, United States
United Hospital Center
RECRUITING

Bridgeport, West Virginia, 26330, United States

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Contact Phone: •••-•••-•••• Email: •••••@•••••
University of Nebraska Medical Center
RECRUITING

Omaha, Nebraska, 68198, United States

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University of Oklahoma Health Sciences Center
RECRUITING

Oklahoma City, Oklahoma, 73104, United States

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University of Pittsburgh Cancer Institute (UPCI)
RECRUITING

Pittsburgh, Pennsylvania, 15232, United States

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Contact Phone: •••-•••-••••
University of Utah Sugarhouse Health Center
RECRUITING

Salt Lake City, Utah, 84106, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

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West Virginia University Healthcare
RECRUITING

Morgantown, West Virginia, 26506, United States

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Contact Phone: •••-•••-•••• Email: •••••@•••••
Wexford Health and Wellness Pavilion
RECRUITING

Wexford, Pennsylvania, 15090, United States

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Contact Email: •••••@•••••
Wheeling Hospital/Schiffler Cancer Center
RECRUITING

Wheeling, West Virginia, 26003, United States

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Contact Phone: •••-•••-••••

Conditions

Explore the condition pages connected to this study.

HEAD AND NECK SQUAMOUS CELL CARCINOMA STAGE I HEAD AND NECK CUTANEOUS SQUAMOUS CELL CARCINOMA AJCC V8 STAGE II HEAD AND NECK CUTANEOUS SQUAMOUS CELL CARCINOMA AJCC V8 STAGE III HEAD AND NECK CUTANEOUS SQUAMOUS CELL CARCINOMA AJCC V8 STAGE IV HEAD AND NECK CUTANEOUS SQUAMOUS CELL CARCINOMA AJCC V8