One-Shot hope for blinding eye disease? new trial underway
NCT ID NCT07215234
First seen Jun 27, 2026 · Last updated Jul 02, 2026 · Updated 2 times
Summary
This study tests a single injection into the eye of a new drug (SAR446597) for people with geographic atrophy, a progressive form of age-related macular degeneration that causes vision loss. About 104 participants aged 60 and older will be followed for 2 years, with an optional 3-year extension, to check safety and whether the treatment slows the growth of the damaged area. The goal is to control the disease, not cure it, as ongoing management is expected.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Associated Retina Consultants - Peoria- Site Number : 8400011
RECRUITINGPeoria, Arizona, 85381, United States
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Austin Clinical Research - Austin - Anderson Mill Road- Site Number : 8400007
RECRUITINGAustin, Texas, 78750, United States
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Cumberland Valley Retina Consultants - Hagerstown- Site Number : 8400003
RECRUITINGHagerstown, Maryland, 21740, United States
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Investigational Site Number : 0360001
RECRUITINGEast Melbourne, Victoria, 3002, Australia
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Investigational Site Number : 0360002
RECRUITINGAdelaide, South Australia, 5000, Australia
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Investigational Site Number : 0360003
RECRUITINGSydney, New South Wales, 2000, Australia
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Mid Atlantic Retina - Bethlehem- Site Number : 8400031
RECRUITINGBethlehem, Pennsylvania, 18017-9412, United States
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Oregon Retina- Site Number : 8400017
RECRUITINGEugene, Oregon, 97401, United States
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Retina Consultants of Austin- Site Number : 8400015
RECRUITINGAustin, Texas, 78705, United States
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Retina Consultants of Texas - Bellaire- Site Number : 8400019
RECRUITINGBellaire, Texas, 77401, United States
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Retina Foundation of the Southwest- Site Number : 8400001
RECRUITINGDallas, Texas, 75231, United States
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Retina Macula Institute of Arizona- Site Number : 8400028
RECRUITINGScottsdale, Arizona, 85255, United States
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Retina Vitreous Associates of Florida - St. Petersburg- Site Number : 8400002
RECRUITINGSt. Petersburg, Florida, 33711, United States
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Retinal Consultants of Texas - San Antonio- Site Number : 8400012
RECRUITINGSan Antonio, Texas, 78240, United States
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Texas Retina Associates - Dallas- Site Number : 8400006
RECRUITINGDallas, Texas, 75231, United States
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The Retina Group of Washington - Chevy Chase- Site Number : 8400009
RECRUITINGChevy Chase, Maryland, 20815, United States
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University Retina - Lemont- Site Number : 8400005
RECRUITINGLemont, Illinois, 60439, United States
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Vitreo Retinal Associates - Gainesville- Site Number : 8400004
RECRUITINGGainesville, Florida, 32607, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- New cell therapy aims to slow vision loss in retinal disease
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- Gene therapy injection aims to halt blinding eye disease