One-Shot hope for blinding eye disease? new trial underway

NCT ID NCT07215234

First seen Jun 27, 2026 · Last updated Jul 02, 2026 · Updated 2 times

Summary

This study tests a single injection into the eye of a new drug (SAR446597) for people with geographic atrophy, a progressive form of age-related macular degeneration that causes vision loss. About 104 participants aged 60 and older will be followed for 2 years, with an optional 3-year extension, to check safety and whether the treatment slows the growth of the damaged area. The goal is to control the disease, not cure it, as ongoing management is expected.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Associated Retina Consultants - Peoria- Site Number : 8400011

    RECRUITING

    Peoria, Arizona, 85381, United States

  • Austin Clinical Research - Austin - Anderson Mill Road- Site Number : 8400007

    RECRUITING

    Austin, Texas, 78750, United States

  • Cumberland Valley Retina Consultants - Hagerstown- Site Number : 8400003

    RECRUITING

    Hagerstown, Maryland, 21740, United States

  • Investigational Site Number : 0360001

    RECRUITING

    East Melbourne, Victoria, 3002, Australia

  • Investigational Site Number : 0360002

    RECRUITING

    Adelaide, South Australia, 5000, Australia

  • Investigational Site Number : 0360003

    RECRUITING

    Sydney, New South Wales, 2000, Australia

  • Mid Atlantic Retina - Bethlehem- Site Number : 8400031

    RECRUITING

    Bethlehem, Pennsylvania, 18017-9412, United States

  • Oregon Retina- Site Number : 8400017

    RECRUITING

    Eugene, Oregon, 97401, United States

  • Retina Consultants of Austin- Site Number : 8400015

    RECRUITING

    Austin, Texas, 78705, United States

  • Retina Consultants of Texas - Bellaire- Site Number : 8400019

    RECRUITING

    Bellaire, Texas, 77401, United States

  • Retina Foundation of the Southwest- Site Number : 8400001

    RECRUITING

    Dallas, Texas, 75231, United States

  • Retina Macula Institute of Arizona- Site Number : 8400028

    RECRUITING

    Scottsdale, Arizona, 85255, United States

  • Retina Vitreous Associates of Florida - St. Petersburg- Site Number : 8400002

    RECRUITING

    St. Petersburg, Florida, 33711, United States

  • Retinal Consultants of Texas - San Antonio- Site Number : 8400012

    RECRUITING

    San Antonio, Texas, 78240, United States

  • Texas Retina Associates - Dallas- Site Number : 8400006

    RECRUITING

    Dallas, Texas, 75231, United States

  • The Retina Group of Washington - Chevy Chase- Site Number : 8400009

    RECRUITING

    Chevy Chase, Maryland, 20815, United States

  • University Retina - Lemont- Site Number : 8400005

    RECRUITING

    Lemont, Illinois, 60439, United States

  • Vitreo Retinal Associates - Gainesville- Site Number : 8400004

    RECRUITING

    Gainesville, Florida, 32607, United States

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