New drug combo aims to speed blood recovery in cancer transplants

NCT ID NCT07362810

Recruiting now Disease control Sponsor: Fudan University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 2 trial tests whether adding IL-11 to the standard drug G-CSF helps blood cells recover faster after a stem cell transplant in people with multiple myeloma or lymphoma. About 224 adults will receive either the combination or G-CSF alone before their transplant. The goal is to see if the combo shortens the time for white blood cells and platelets to return to safe levels, reducing the need for transfusions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: G-CSF and IL-11 (drugs to stimulate blood cell production)
What this could lead to: If successful, this combination could speed up recovery of platelets and red blood cells after transplant, reducing the need for transfusions.
What could go wrong: This is a mid-stage trial with 224 participants, so results are not yet proven. The added drug may cause side effects or not improve outcomes significantly.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

hematopoietic and lymphoid system neoplasm lymphoma plasma cell myeloma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEMATO-ONCOLOGIC PATIENTS HEMATOPOETIC STEM CELL TRANSPLANTATION MOBILIZATION OF HEMATOPOIETIC STEM CELLS (HSC) TO PERIPHERAL BLOOD (PB)

Contacts and locations

Locations

Huadong Hospital, Fudan University
RECRUITING

Shanghai, Shanghai Municipality, 200040, China
The first affiliated hospital of Zhengzhou university
RECRUITING

Zhengzhou, Henan, 450052, China
Tongji Hospital of Tongji University
RECRUITING

Shanghai, Shanghai Municipality, 200065, China

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