Stem cell donation: one shot or two? trial seeks best way to mobilize cells
NCT ID NCT07692841
First seen Jul 09, 2026 · Last updated Jul 16, 2026 · Updated 3 times
Summary
This trial tests whether giving the drug G-CSF as one daily injection or two smaller injections works better for collecting stem cells from healthy donors. The goal is to find the safest and most effective dosing schedule for donors of all ages. The study involves 560 healthy volunteers who will receive either a single or divided daily dose for up to 7 days.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Granulocyte colony-stimulating factor (G-CSF)
- What this could lead to
- If one dosing schedule proves better, it could make stem cell donation more efficient and comfortable for healthy donors, improving transplant success.
- What could go wrong
- This is a single trial focused on Asian donors, so results may not apply to all populations. G-CSF can cause bone pain and other side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Jinhua Central Hospital
RECRUITINGJinhua, Zhejiang, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Sir Run Run Shaw Hospital, Zhejiang University School of Medicine
RECRUITINGHangzhou, Zhejiang, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The Affiliated People's Hospital of Ningbo University
RECRUITINGNingbo, Zhejiang, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The First Affiliated Hospital of Ningbo University
RECRUITINGNingbo, Zhejiang, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The First Affiliated Hospital of Wenzhou Medical University
RECRUITINGWenzhou, Zhejiang, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The First Affiliated Hospital, Zhejiang University School of Medicine.
RECRUITINGHangzhou, Zhejiang, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The Second Affiliated Hospital of Zhejiang University School of Medicine
RECRUITINGHangzhou, Zhejiang, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Xiangya Hospital of Central South University
RECRUITINGChangsha, Hunan, China
Contact Phone: •••-•••-•••• Email: •••••@•••••