New biosimilar shows promise for treating wet macular degeneration

NCT ID NCT04522167

Completed Disease control Sponsor: Bioeq GmbH Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a new drug called FYB203, which is a biosimilar (a close copy) of the existing medication Eylea, for people with wet age-related macular degeneration (AMD), a leading cause of vision loss. The trial involved 434 participants and compared how well FYB203 worked versus Eylea in improving vision over 8 weeks. The goal was to see if FYB203 is as safe and effective as Eylea, offering a potentially more affordable treatment option for this chronic eye condition.

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Conditions

The condition(s) this trial relates to.

wet macular degeneration

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NEOVASCULAR AGE-RELATED MACULAR DEGENERATION

Contacts and locations

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Locations

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Sofia, Bulgaria
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Stara Zagora, Bulgaria
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Hradec Králové, Czechia
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Ostrava, Czechia
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Pardubice, Czechia
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Prague, Czechia
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Sokolov, Czechia
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Budapest, Hungary
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Debrecen, Hungary
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Pécs, Hungary
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Szeged, Hungary
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Székesfehérvár, Hungary
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Tatabánya, Hungary
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Zalaegerszeg, Hungary
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Haifa, Israel
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Jerusalem, Israel
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Kfar Saba, Israel
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Petah Tikva, Israel
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Rehovot, Israel
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Rishon LeZiyyon, Israel
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Tel Aviv, Israel
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Bologna, Italy
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Florence, Italy
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Milan, Italy
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Roma, Italy
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Rozzano, Italy
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Udine, Italy
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Akita, Japan
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Amagasaki, Japan
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Asahikawa, Japan
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Chiyoda City, Japan
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Chūō, Japan
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Fukuoka, Japan
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Fukushima, Japan
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Hamamatsu, Japan
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Himeji, Japan
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Hirakata, Japan
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Kita-ku, Japan
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Kurume, Japan
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Meguro City, Japan
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Nagasaki, Japan
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Nagoya, Japan
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Sapporo, Japan
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Shinjuku-Ku, Japan
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Suita, Japan
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Toride, Japan
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Yokosuka, Japan
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Bielsko-Biala, Poland
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Bydgoszcz, Poland
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Krakow, Poland
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Lodz, Poland
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Olsztyn, Poland
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Tarnów, Poland
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Warsaw, Poland
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Chelyabinsk, Russia
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Kazan', Russia
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Moscow, Russia
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Novosibirsk, Russia
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Saint Petersburg, Russia
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Kharkiv, Ukraine
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Kherson, Ukraine
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Kropyvnytskyi, Ukraine
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Lutsk, Ukraine
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Odesa, Ukraine
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Poltava, Ukraine
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Zaporizhzhya, Ukraine