New drug FWY003 aims to halt blinding eye disease

NCT ID NCT07441642

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This Phase 2 trial tests FWY003, an experimental drug, in 272 people with geographic atrophy (a form of advanced age-related macular degeneration). The goal is to see if different doses can slow the growth of damaged areas in the eye and preserve vision. Participants receive either FWY003 or a placebo by injection, and researchers will monitor safety and changes in eyesight over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

FWY003

What this could lead to

If successful, this could lead to a treatment that slows vision loss from geographic atrophy, helping people with age-related macular degeneration maintain sight longer.

What could go wrong

This is an early Phase 2 trial with only 272 participants, so results may not confirm effectiveness. The drug may not slow disease progression or could cause side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

age-related macular degeneration

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-••••

Locations

  • Advanced Research LLC

    RECRUITING

    Boynton Beach, Florida, 33437, United States

    Contact Email: •••••@•••••

    Contact

  • Advanced Research LLC

    RECRUITING

    Deerfield Beach, Florida, 33064, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • California Retina Consultants

    RECRUITING

    Santa Barbara, California, 93103, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Columbia University Medical Center

    RECRUITING

    New York, New York, 10032, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Emanuelli Research and Development Center LLC

    RECRUITING

    Arecibo, 00612, Puerto Rico

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Erie Retina Research LLC

    RECRUITING

    Erie, Pennsylvania, 16505, United States

    Contact

    Contact Email: •••••@•••••

  • NJ Retina

    RECRUITING

    Toms River, New Jersey, 08755, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • New York Eye and Ear Infirmary of Mount Sinai

    RECRUITING

    New York, New York, 10003, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Novartis Investigative Site

    RECRUITING

    Albury, New South Wales, 2640, Australia

  • Novartis Investigative Site

    RECRUITING

    Parramatta, New South Wales, 2150, Australia

  • Novartis Investigative Site

    RECRUITING

    Strathfield, New South Wales, 2135, Australia

  • Novartis Investigative Site

    RECRUITING

    East Melbourne, Victoria, 3002, Australia

  • Novartis Investigative Site

    RECRUITING

    Sofia, 1618, Bulgaria

  • Novartis Investigative Site

    RECRUITING

    Ottawa, Ontario, K2B 7E9, Canada

  • Novartis Investigative Site

    RECRUITING

    Prague, 100 34, Czechia

  • Novartis Investigative Site

    RECRUITING

    Prague, 128 08, Czechia

  • Novartis Investigative Site

    RECRUITING

    Lyon, Rhone, 69004, France

  • Novartis Investigative Site

    RECRUITING

    Créteil, 94000, France

  • Novartis Investigative Site

    RECRUITING

    Dijon, 21000, France

  • Novartis Investigative Site

    RECRUITING

    Paris, 75940, France

  • Novartis Investigative Site

    RECRUITING

    Ludwigshafen, Germany, 67063, Germany

  • Novartis Investigative Site

    RECRUITING

    Bonn, 53105, Germany

  • Novartis Investigative Site

    RECRUITING

    Tübingen, 72076, Germany

  • Novartis Investigative Site

    RECRUITING

    Pécs, Baranya, 7621, Hungary

  • Novartis Investigative Site

    RECRUITING

    Debrecen, Hajdu Bihar Megye, 4032, Hungary

  • Novartis Investigative Site

    RECRUITING

    Budapest, H-1083, Hungary

  • Novartis Investigative Site

    RECRUITING

    Milan, MI, 20132, Italy

  • Novartis Investigative Site

    RECRUITING

    Roma, RM, 00184, Italy

  • Novartis Investigative Site

    RECRUITING

    Bydgoszcz, Kuyavian-Pomeranian Voivodeship, 85 631, Poland

  • Novartis Investigative Site

    RECRUITING

    Krakow, 31-070, Poland

  • Novartis Investigative Site

    RECRUITING

    Cluj-Napoca, Cluj, 400006, Romania

  • Novartis Investigative Site

    RECRUITING

    Bucharest, 011658, Romania

  • Novartis Investigative Site

    RECRUITING

    Santiago Compostela, A Coruna, 15706, Spain

  • Novartis Investigative Site

    RECRUITING

    Burjassot, Valencia, 46100, Spain

  • Opthamalic Consultants of Boston

    RECRUITING

    Boston, Massachusetts, 02114, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Retina Consultants TX Rsrch Ctr

    RECRUITING

    Bellaire, Texas, 77401, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Retina Consultants of Houston PA

    RECRUITING

    Houston, Texas, 77030, United States

    Contact

    Contact Email: •••••@•••••

  • Retina Consultants of Texas

    RECRUITING

    Katy, Texas, 77494, United States

    Contact

    Contact Email: •••••@•••••

  • Retina Vitreous Associates of Florida

    RECRUITING

    St. Petersburg, Florida, 33711, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Retinal Consultants Medical Group Inc

    RECRUITING

    Sacramento, California, 95841, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Salehi Retina Institute

    RECRUITING

    Huntington Beach, California, 92647, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact