New pill aims to slow vision loss from dry macular degeneration

NCT ID NCT07606365

Not yet recruiting Disease control Sponsor: Sitala Bio LTD Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests an oral drug called STL303 for geographic atrophy, a form of dry age-related macular degeneration that causes a blind spot in central vision. About 300 adults aged 60 and older will receive either STL303 or a placebo pill for up to 2 years. The goal is to see if the drug safely slows the loss of cells in the retina and preserves eyesight.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: STL303 (oral drug)
What this could lead to: If it works, this could slow vision loss from geographic atrophy, helping people keep their central eyesight longer.
What could go wrong: This is an early Phase 2 trial with only 300 people. The drug may not slow vision loss or could cause side effects. Success is not guaranteed.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

age-related macular degeneration dry age related macular degeneration Geographic Atrophy macular degeneration

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GEOGRAPHIC ATROPHY

Contacts and locations

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Study contacts

Contact

Email: •••••@•••••

Locations

Adelaide Eye and Retina Centre

Adelaide, South Australia, 5000, Australia
Associated Vitreoretinal and Uveitis Consultants

Carmel, Indiana, 46032, United States
Augenarzte Bern Zentrum Marktgasse

Bern, 3011, Switzerland
Axon Clinical s.r.o.

Prague, Prague, 150 00, Czechia
Berner Augenklinik

Bern, 3007, Switzerland
Buenos Aires Macula S.A

Buenos Aires, Buenos Aires, 1061, Argentina
California Retina Consultants

Bakersfield, California, 93309, United States
Centro Medico Viamonte SRL

Buenos Aires, Buenos Aires, C1120AAC, Argentina
Centro Oftalmologico Dr. Charles S.A.

Buenos Aires, Ciudad Autonoma Buenos Aires, C1121ABB, Argentina
Centro Privado de Ojos

Ciudad Autonoma Buenos Aires, Ciudad Autonoma Buenos Aires, C1033AAW, Argentina
Centro de Ojos Quilmes

Quilmes, Buenos Aires, 1878, Argentina
Centro de la Vision

Salta, Salta Province, 4400, Argentina
Centrovision Mendoza SA

Mendoza, Mendoza Province, 5500, Argentina
Centrum Diagnostyki i Mikrochirurgii Oka LENS

Olsztyn, 10-424, Poland
Centrum Medyczne

Wałbrzych, 58304, Poland
Centrum Medyczne Dietla 19

Krakow, 31-070, Poland
Centrum Zdrowia MDM

Warsaw, 00-189, Poland
Cerulea Pty Ltd

East Melbourne, Victoria, 3002, Australia
Clinical Medical Research Sp. z o.o.

Katowice, 40-156, Poland
Cumberland Valley Retina Consultants,P.C.

Hagerstown, Maryland, 21740, United States
Ente Ospedaliero Cantonale

Bellinzona, 6500, Switzerland
Erie Retina Research

Erie, Pennsylvania, 16507, United States
Eye Clinic of Wisconsin

Wausau, Wisconsin, 54403, United States
Fakultni nemocnice Kralovske Vinohrady

Prague, Prague, 100 34, Czechia
Florida Retina Institute

Wildwood, Florida, 34785, United States
Grupo Laser Visión - Rosario Eximer Laser Visión

Rosario, Santa Fe Province, 2000, Argentina
Hospital Britanico de Buenos Aires

Buenos Aires, Ciudad Autonoma Buenos Aires, 1008, Argentina
IMOC Instituto de Microcirugia Ocular Cordoba

Córdoba, Córdoba Province, X5000, Argentina
Instituoto Oftalmologico de Buenos Aires S.A.

Buenos Aires, Ciudad Autonoma Buenos Aires, C1056, Argentina
Kaiser Permanente - Oakland

Oakland, California, 94612, United States
Long Island and Queens Vitreoretinal Consultants of NY, P.C.

Hauppauge, New York, 11788, United States
Mid Atlantic Retina Specialists

Hagerstown, Maryland, 21740, United States
Northeast Wisconsin Retina Associates

Appleton, Wisconsin, 54914, United States
OFTEX, s.r.o.

Pardubice, Prague, 530 02, Czechia
Ophthalmic Consultants of Boston

Waltham, Massachusetts, 02451, United States
Poznanskie Centrum Wzroku sp z o o

Poznan, 60-538, Poland
Prywatna Klinika Okulistyczna OFTALMIKA

Bydgoszcz, 85-631, Poland
Queensland Eye Institute

South Brisbane, Queensland, 4101, Australia
Retina Consultants of Texas

Bellaire, Texas, 77401, United States
Retina Consultants of Texas

Schertz, Texas, 78154, United States
Retina Group of New England, PC

Waterford, Connecticut, 06385, United States
Retina Specialists of Colorado

Aurora, Colorado, 80012, United States
Retina Vitreous Associates of Florida

St. Petersburg, Florida, 33711, United States
Retina-Vitreous Associates Medical Group

Beverly Hills, California, 90211, United States
Royal Melbourne Hospital

Parkville, Victoria, 3050, Australia
Royal Victoria Infirmary

Newcastle upon Tyne, Tyne & Wear, NE1 4LP, United Kingdom
Southampton General Hospital

Southampton, Hampshire, SO16 6YD, United Kingdom
Specjalistyczna Praktyka Lekarska Prof. Edward Wylęgała

Katowice, 40-594, Poland
Specjalistyczny Osrodek Okulistyczny Oculomedica

Bydgoszcz, 00-189, Poland
Stadtspital Triemli

Zurich, 8063, Switzerland
Star Vision Research

Burleson, Texas, 76028, United States
Swiss Visio Montchoisi

Lausanne, 1006, Switzerland
Sydney Eye Hospital

Sydney, New South Wales, 2000, Australia
Sydney West Retina

Westmead, New South Wales, 2145, Australia
Szpital Swietego Lukasza S. A.

Bielsko-Biala, 43-309, Poland
Tennessee Retina, PC

Nashville, Tennessee, 37203, United States
The Retina Clinic London

London, Greater London, W1G 7LB, United Kingdom
University Hospitals of Leicester NHS Trust

Leicester, Leicestershire, LE5 4PW, United Kingdom
University Retina and Macula Associates, P.C.

Lemont, Illinois, 60439, United States
Vista Augenklinik Binningen

Binningen, 4102, Switzerland

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