Cancer drug futibatinib gets a safety check in Long-Term rollover study

NCT ID NCT06506955

First seen Jun 27, 2026 · Last updated Jul 29, 2026 · Updated 2 times

Summary

This study is for people with advanced or metastatic cancer who have already been taking futibatinib in a previous study and are still benefiting from it. The goal is to keep giving them the drug (alone or with fulvestrant) and watch for any side effects over a longer period. Only 15 participants are expected, and the study is open-label, meaning everyone knows what treatment they are getting.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
futibatinib (alone or with fulvestrant)
What this could lead to
If successful, this study could show that long-term futibatinib treatment is safe and continues to control advanced cancer in patients who already responded.
What could go wrong
This is a very small rollover study (15 patients) with no control group, so results may not apply broadly. Side effects from long-term use are still being evaluated.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Centro Integral Oncologico

    Madrid, 28050, Spain

  • Hospital Universitari, Vall d'Hebron

    Barcelona, 8035, Spain

  • Institut De Cancerologie Strasbourg

    Strasbourg, 67033, France

  • Institut Paoli-Calmettes

    Marseille, 13009, France

  • Royal Marsden NHS Foundation Trust

    London, SW3 6JJ, United Kingdom

  • Sarah Cannon Research Institute UK

    London, W1G 6AD, United Kingdom

  • Severance Hospital

    Seoul, 3722, South Korea

  • University College London Hospitals NHS Foundation Trust

    London, W1T 7HA, United Kingdom

  • University of California, San Francisco (UCSF)

    San Francisco, California, 94143, United States

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