New combo therapy for bladder cancer shows promise but trial halted

NCT ID NCT04601857

First seen Jan 09, 2026 · Last updated May 15, 2026 · Updated 19 times

Summary

This study tested a combination of two drugs—futibatinib and pembrolizumab—in people with advanced or spreading bladder cancer who couldn't receive standard chemotherapy. The goal was to see if the combo could shrink tumors and be safe. The trial was stopped early after enrolling 43 participants, and results are limited.

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Contacts and locations

Locations

  • ALTHAIA, Xarxa Assistencial Universitària de Manresa

    Manresa, Brcelona, 8243, Spain

  • Centre Georges-François Leclerc

    Dijon, Côte d'Or, 21079, France

  • Centre Leon Berard - departement d'oncologie medicale

    Lyon, Rhone, 69373, France

  • Centre Regional de Lutte Contre le Cancer de Lorraine

    Vandœuvre-lès-Nancy, 54500, France

  • Comprehensive Care Centers of Nevada

    Las Vegas, Nevada, 89148, United States

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Henry Ford Hospital

    Detroit, Michigan, 48202, United States

  • Hospital Clinic de Barcelona

    Barcelona, 08036, Spain

  • Hospital Universitario HMN Sanchinarro

    Madrid, 28050, Spain

  • Hospital Universitario Marqués de Valdecilla

    Santander, 39008, Spain

  • Hospital Universitario Reina Sofia

    Córdoba, 14004, Spain

  • Hospital Universitario Vall d'Hebrón

    Barcelona, 8035, Spain

  • Hospital de La Santa Creu i Sant Pau

    Barcelona, 8025, Spain

  • Hospital la Fe

    Valencia, 46026, Spain

  • ICANS - Institut de cancérologie de Strasbourg Europe

    Strasbourg, Bas-Rhin, 67200, France

  • Institut De Cancerologie Gustave Roussy

    Villejuif, 94805, France

  • Institut Paoli Calmettes - Hôpital de jour

    Marseille, Bouches-du-Rhône, 13273, France

  • UCSF Helen Diller Family Comprehensive Cancer Center

    San Francisco, California, 94158, United States

Conditions

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