New PET tracer could spot hidden fungal infections

NCT ID NCT07704333

First seen Jul 15, 2026 · Last updated Jul 17, 2026 · Updated 2 times

Summary

This Phase 1 trial tests a new radioactive tracer called [18F]-Fluorocellobiose ([18F]FCB) for PET/CT scans. The goal is to see if it can help find invasive mold infections in the body. The study includes healthy volunteers and people with known fungal infections. Participants receive the tracer through an IV and undergo imaging to measure how it travels through the body and collects at infection sites.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
a radioactive tracer called [18F]-Fluorocellobiose ([18F]FCB) for PET/CT scans
What this could lead to
If successful, this could provide a new way to detect fungal infections in the body using imaging scans, potentially leading to earlier diagnosis and treatment.
What could go wrong
This is an early Phase 1 trial focused on safety and imaging properties, not on treatment outcomes. The tracer may not reliably distinguish infections from other conditions.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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