Washing the chest with antifungals: a new hope for deadly fungal infections?

NCT ID NCT07337993

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether washing the chest cavity with the antifungal drug voriconazole can help treat a rare but serious fungal infection of the lung lining. It includes 50 patients who either get the wash before surgery or as a standalone treatment if they are too sick for surgery. The goal is to see if this approach improves lung expansion and reduces complications.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

voriconazole

What this could lead to

If it works, this could offer a less invasive treatment option for fungal chest infections, especially for patients too sick for surgery.

What could go wrong

This is a small, early study with only 50 participants. It may not show clear benefits, and there are risks like allergic reactions or complications from the procedure.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

fungal lung infectious disease pleural empyema

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Services Hospital Lahore

    RECRUITING

    Lahore, Punjab Province, 54000, Pakistan

    Contact Phone: •••-•••-•••• Email: •••••@•••••