Breakthrough combo aims to beat hepatitis b for good

NCT ID NCT05769816

First seen Sep 30, 2025 · Last updated May 15, 2026 · Updated 29 times

Summary

This study tests a new combination of drugs to help people with chronic hepatitis B achieve a 'functional cure'—meaning the virus is no longer active in the body. About 120 adults aged 18-70 will receive an immune-boosting drug (anti-PD-1 antibody) along with standard antivirals. The goal is to see if this approach can clear the hepatitis B surface antigen (HBsAg) in more than half of patients, improving on current success rates of 15% or less.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The 2nd affiliated Hospital of Chongqing Medical University

    RECRUITING

    Chongqing, Chongqing Municipality, 400010, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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