Could a single cell therapy tame lupus and other autoimmune diseases?

NCT ID NCT06308978

First seen Nov 01, 2025 · Last updated Apr 28, 2026 · Updated 31 times

Summary

This early-stage trial tests a new treatment called FT819 for people with certain autoimmune diseases like lupus, vasculitis, myositis, and scleroderma. The treatment aims to target and control the immune cells that cause these diseases. The study will check if FT819 is safe and find the best dose, involving up to 244 participants aged 12 to 70 whose disease has not responded to at least two prior treatments.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cambridge University Hospitals NHS Foundation Trust

    RECRUITING

    Cambridge, CB2 0QQ, United Kingdom

  • Children's Hospital Los Angeles Division Of Rheumatology

    RECRUITING

    Los Angeles, California, 90027, United States

  • Duke University Health System

    RECRUITING

    Durham, North Carolina, 27705, United States

  • Hôpital La Pitié Salpêtrière

    RECRUITING

    Paris, 75013, France

  • Jefferson Einstein Hospital Philadelphia

    RECRUITING

    Philadelphia, Pennsylvania, 19141, United States

  • Manchester University NHS Foundation Trust

    RECRUITING

    Manchester, Greater Manchester, M139WL, United Kingdom

  • MetroHealth

    RECRUITING

    Cleveland, Ohio, 44109, United States

  • Montefiore Medical Center

    RECRUITING

    New York, New York, 10467, United States

  • Providence Medical Foundation

    RECRUITING

    Fullerton, California, 92835, United States

  • Regional One Health

    RECRUITING

    Memphis, Tennessee, 38103, United States

  • University College of London Hospitals NHS Trust (UCLH)

    RECRUITING

    London, NW1 2PQ, United Kingdom

  • University of California Irvine

    RECRUITING

    Irvine, California, 92868, United States

  • University of California San Francisco

    RECRUITING

    San Francisco, California, 94110, United States

  • University of Minnesota Medical School

    RECRUITING

    Minneapolis, Minnesota, 55455, United States

  • University of Nebraska Medical Center

    RECRUITING

    Omaha, Nebraska, 68198, United States

  • University of Oklahoma

    RECRUITING

    Oklahoma City, Oklahoma, 73019, United States

  • Uppsala University

    RECRUITING

    Uppsala, Uppland, 752 37, Sweden

Conditions

Explore the condition pages connected to this study.