Scientists test One-Shot gene therapy to silence root cause of Muscle-Wasting disease

NCT ID NCT06907875

Summary

This early-stage study is testing a new, one-time gene therapy called EPI-321 in adults with FSHD, a genetic muscle-wasting disease. The main goal is to find out if the treatment is safe and what dose is best, while also looking for early signs that it might be working. About 12 participants will receive the therapy through an IV and be closely monitored for up to five years.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • David Geffen School of Medicine at University of California, Los Angeles

    RECRUITING

    Los Angeles, California, 90095, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Pacific Clinical Research Network

    RECRUITING

    Auckland, 0622, New Zealand

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Rare Disease Research

    RECRUITING

    Atlanta, Georgia, 303329, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Royal Alfred Hospital

    NOT_YET_RECRUITING

    Sydney, New South Wales, 2050, Australia

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Massachusetts Chan Medical School

    RECRUITING

    Worcester, Massachusetts, 01605, United States

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Utah Program for Inherited Neuromuscular Disorders - University of Utah

    RECRUITING

    Salt Lake City, Utah, 84112, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.