New combo therapy shows promise for tough prostate cancer

NCT ID NCT06909825

First seen Oct 31, 2025 · Last updated May 14, 2026 · Updated 29 times

Summary

This study tests a new drug combination (FPI-2265 and olaparib) in 85 men with advanced prostate cancer that no longer responds to hormone therapy. The goal is to see if the treatment can shrink tumors and lower PSA levels while monitoring side effects. Participants must have tried at least one prior hormone therapy and be in relatively good health.

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Contacts and locations

Locations

  • Icon Cancer Centre Kurralta Park

    Kurralta Park, South Australia, 5037, Australia

  • Macquarie University Hospital

    Macquarie Park, New South Wales, 2113, Australia

  • Peter MacCallum Cancer Center

    Melbourne, Victoria, 3000, Australia

  • Princess Alexandra Hospital

    Woolloongabba, Queensland, 4102, Australia

Conditions

Explore the condition pages connected to this study.