Could an HIV drug soothe stubborn throat reflux?
NCT ID NCT04383262
First seen Nov 01, 2025 · Last updated May 02, 2026 · Updated 22 times
Summary
This study tests whether fosamprenavir, an FDA-approved HIV medication, can treat laryngopharyngeal reflux (LPR) — a condition causing chronic cough, hoarseness, and throat clearing. About 104 adults with LPR who did not improve with standard acid-reducing therapy will receive either the drug or a placebo for 12 weeks. The goal is to see if blocking a digestive enzyme called pepsin can relieve symptoms and prevent throat damage.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Froedtert Hospital
Milwaukee, Wisconsin, 53226, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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