Experimental drug aims to halt 'Second Skeleton' disease
NCT ID NCT05394116
Summary
This Phase 3 trial is testing an experimental drug called garetosmab in adults with fibrodysplasia ossificans progressiva (FOP), a rare disease that causes soft tissues to turn into bone. The main goals are to see if the drug is safe and if it can reduce the number of new abnormal bone growths (lesions) and painful flare-ups. The study is comparing the drug against a placebo in 63 participants over 84 weeks.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for FIBRODYSPLASIA OSSIFICANS PROGRESSIVA are added.
By submitting, you agree to our Terms of use
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Amsterdam University Medical Center
Amsterdam, North Holland, 1081 HV, Netherlands
-
Clinica Universidad de La Sabana
Chía, Cundinamarca, 140013, Colombia
-
HUS Children and Adolescents Park Hospital Clinical Trial Unit
Helsinki, Stenbäckinkatu 11, 00029, Finland
-
Hopital Lariboisiere
Paris, 75010, France
-
Hospital Israelita Albert Einstein
São Paulo, 05652-900, Brazil
-
Hospital Kuala Lampur
Kuala Lumpur, 50586, Malaysia
-
Hospital Universitario Ramon y Cajal
Madrid, 28034, Spain
-
Hôpital Lapeyronie
Montpellier, 34090, France
-
IRCCS Istituto Giannina Gaslini
Genoa, 16147, Italy
-
Kyushu University Hospital
Fukuoka, 812-8582, Japan
-
Nagoya University Hospital
Nagoya, Aichi-ken, 466-8560, Japan
-
Oita University Hospital
Yufu, Oita Prefecture, 879-5593, Japan
-
Queen Mary Hospital
Hong Kong, 22553838, Hong Kong
-
Royal National Orthropaedic Hospital NHS Trust
Middlesex, Greater London, HA7 4LP, United Kingdom
-
Royal North Shore Hospital
St Leonards, New South Wales, 2065, Australia
-
Seoul National University Hospital
Seoul, 03080, South Korea
-
Szpital Centrum Medyczne Medyk
Rzeszów, Podkarpackie Voivodeship, 35-326, Poland
-
Tongji Hospital of Tongji University
Shanghai, 200065, China
-
Universidad de Concepcion
Concepción, Bio Bio, 4030000, Chile
-
University of California Los Angeles (UCLA) Medical Center
Los Angeles, California, 90095, United States
-
University of Cape Town
Rondebosch, Cape Town, 7700, South Africa
-
Vanderbilt University Medical Center
Nashville, Tennessee, 37232, United States
Conditions
Explore the condition pages connected to this study.