Scientists test adding a third drug to standard lymphoma treatment

NCT ID NCT01286272

Completed Disease control Sponsor: National Cancer Institute (NCI) Source: ClinicalTrials.gov ↗

Summary

This study aimed to see if adding the drug bortezomib to a standard two-drug combination (ofatumumab and bendamustine) was more effective for people newly diagnosed with a type of slow-growing blood cancer called follicular lymphoma. It involved 135 patients with high-risk disease. The main goal was to see which treatment led to more patients having their cancer completely disappear.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Altru Cancer Center

Grand Forks, North Dakota, 58201, United States
Annie Penn Memorial Hospital

Reidsville, North Carolina, 27320, United States
Benefis Sletten Cancer Institute

Great Falls, Montana, 59405, United States
Billings Clinic Cancer Center

Billings, Montana, 59101, United States
Cancer Care Specialists of Illinois - Decatur

Decatur, Illinois, 62526, United States
Castle Medical Center

Kailua, Hawaii, 96734, United States
Central Care Cancer Center - Bolivar

Bolivar, Missouri, 65613, United States
Cone Health Cancer Center

Greensboro, North Carolina, 27403, United States
Corewell Health Grand Rapids Hospitals - Butterworth Hospital

Grand Rapids, Michigan, 49503, United States
CoxHealth South Hospital

Springfield, Missouri, 65807, United States
Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center

Lebanon, New Hampshire, 03756, United States
Decatur Memorial Hospital

Decatur, Illinois, 62526, United States
ECU Health Oncology Kinston

Kinston, North Carolina, 28501, United States
Eastern Maine Medical Center

Bangor, Maine, 04401, United States
Fairview Ridges Hospital

Burnsville, Minnesota, 55337, United States
Fairview Southdale Hospital

Edina, Minnesota, 55435, United States
Fort Wayne Medical Oncology and Hematology Inc-Parkview

Fort Wayne, Indiana, 46845, United States
Franciscan Health Indianapolis

Indianapolis, Indiana, 46237, United States
Guthrie Medical Group PC-Robert Packer Hospital

Sayre, Pennsylvania, 18840, United States
Harold Alfond Center for Cancer Care

Augusta, Maine, 04330, United States
Hawaii Cancer Care Inc - Waterfront Plaza

Honolulu, Hawaii, 96813, United States
Hawaii Cancer Care Inc-Liliha

Honolulu, Hawaii, 96817, United States
Hematology Oncology Associates of Central New York-East Syracuse

East Syracuse, New York, 13057, United States
Henry Ford Health Saint John Hospital

Detroit, Michigan, 48236, United States
Ingalls Memorial Hospital

Harvey, Illinois, 60426, United States
Iredell Memorial Hospital

Statesville, North Carolina, 28677, United States
Kapiolani Medical Center for Women and Children

Honolulu, Hawaii, 96826, United States
Kettering Medical Center

Kettering, Ohio, 45429, United States
Kootenai Clinic Cancer Services - Post Falls

Post Falls, Idaho, 83854, United States
Kuakini Medical Center

Honolulu, Hawaii, 96817, United States
Long Island Jewish Medical Center

New Hyde Park, New York, 11040, United States
MU Health - University Hospital/Ellis Fischel Cancer Center

Columbia, Missouri, 65212, United States
Memorial Hospital of South Bend

South Bend, Indiana, 46601, United States
Memorial Regional Cancer Center Day Road

Mishawaka, Indiana, 46545, United States
Mercy Health - Saint Anne Hospital

Toledo, Ohio, 43623, United States
Mercy Hospital

Cedar Rapids, Iowa, 52403, United States
Mercy Hospital Oklahoma City

Oklahoma City, Oklahoma, 73120, United States
Mercy Hospital Saint Louis

St Louis, Missouri, 63141, United States
Mercy Hospital Springfield

Springfield, Missouri, 65804, United States
Miami Valley Hospital North

Dayton, Ohio, 45415, United States
Michiana Hematology Oncology PC-Mishawaka

Mishawaka, Indiana, 46545, United States
Michiana Hematology Oncology PC-Westville

Westville, Indiana, 46391, United States
Middlesex Hospital

Middletown, Connecticut, 06457, United States
Minneapolis VA Medical Center

Minneapolis, Minnesota, 55417, United States
Minnesota Oncology Hematology PA-Maplewood

Maplewood, Minnesota, 55109, United States
Missouri Baptist Medical Center

St Louis, Missouri, 63131, United States
Mount Sinai Medical Center

Miami Beach, Florida, 33140, United States
NYP/Weill Cornell Medical Center

New York, New York, 10065, United States
Nevada Cancer Research Foundation NCORP

Las Vegas, Nevada, 89120, United States
North Shore University Hospital

Manhasset, New York, 11030, United States
NorthShore University HealthSystem-Evanston Hospital

Evanston, Illinois, 60201, United States
Northwell Health NCORP

Lake Success, New York, 11042, United States
Northwell Health/Center for Advanced Medicine

Lake Success, New York, 11042, United States
Ohio State University Comprehensive Cancer Center

Columbus, Ohio, 43210, United States
Oncology Associates at Mercy Medical Center

Cedar Rapids, Iowa, 52403, United States
Pali Momi Medical Center

‘Aiea, Hawaii, 96701, United States
Park Nicollet Clinic - Saint Louis Park

Saint Louis Park, Minnesota, 55416, United States
Penobscot Bay Medical Center

Rockport, Maine, 04856, United States
ProMedica Flower Hospital

Sylvania, Ohio, 43560, United States
Providence Portland Medical Center

Portland, Oregon, 97213, United States
Providence Saint Vincent Medical Center

Portland, Oregon, 97225, United States
Queen's Cancer Center - Pearlridge

‘Aiea, Hawaii, 96701, United States
Queen's Medical Center

Honolulu, Hawaii, 96813, United States
Randolph Hospital

Asheboro, North Carolina, 27203, United States
Regions Hospital

Saint Paul, Minnesota, 55101, United States
Saint Alphonsus Cancer Care Center-Boise

Boise, Idaho, 83706, United States
Saint Charles Hospital

Oregon, Ohio, 43616, United States
Saint Francis Cancer Center

Greenville, South Carolina, 29607, United States
Saint Francis Hospital

Greenville, South Carolina, 29601, United States
Saint Helena Hospital

St. Helena, California, 94574, United States
Saint John's Hospital - Healtheast

Maplewood, Minnesota, 55109, United States
Saint Luke's Hospital of Kansas City

Kansas City, Missouri, 64111, United States
Sinai Hospital of Baltimore

Baltimore, Maryland, 21215, United States
Siouxland Regional Cancer Center

Sioux City, Iowa, 51101, United States
Southern Illinois University School of Medicine

Springfield, Illinois, 62702, United States
Spartanburg Medical Center

Spartanburg, South Carolina, 29303, United States
Springfield Clinic

Springfield, Illinois, 62702, United States
Springfield Memorial Hospital

Springfield, Illinois, 62781, United States
State University of New York Upstate Medical University

Syracuse, New York, 13210, United States
Straub Clinic and Hospital

Honolulu, Hawaii, 96813, United States
Toledo Clinic Cancer Centers-Maumee

Maumee, Ohio, 43537, United States
Toledo Clinic Cancer Centers-Toledo

Toledo, Ohio, 43623, United States
Trinity Health Grand Rapids Hospital

Grand Rapids, Michigan, 49503, United States
Trinity Health Saint Joseph Mercy Hospital Ann Arbor

Ann Arbor, Michigan, 48106, United States
UC San Diego Moores Cancer Center

La Jolla, California, 92093, United States
UNC Lineberger Comprehensive Cancer Center

Chapel Hill, North Carolina, 27599, United States
University of Chicago Comprehensive Cancer Center

Chicago, Illinois, 60637, United States
University of Illinois

Chicago, Illinois, 60612, United States
University of Oklahoma Health Sciences Center

Oklahoma City, Oklahoma, 73104, United States
VCU Massey Comprehensive Cancer Center

Richmond, Virginia, 23298, United States
Wake Forest University Health Sciences

Winston-Salem, North Carolina, 27157, United States
Washington University School of Medicine

St Louis, Missouri, 63110, United States
Wayne Memorial Hospital

Goldsboro, North Carolina, 27534, United States
Weiss Memorial Hospital

Chicago, Illinois, 60640, United States
West Virginia University Healthcare

Morgantown, West Virginia, 26506, United States
Wilcox Memorial Hospital and Kauai Medical Clinic

Lihue, Hawaii, 96766, United States

Conditions

Explore the condition pages connected to this study.

ANN ARBOR STAGE III GRADE 1 FOLLICULAR LYMPHOMA ANN ARBOR STAGE III GRADE 2 FOLLICULAR LYMPHOMA ANN ARBOR STAGE III GRADE 3 FOLLICULAR LYMPHOMA ANN ARBOR STAGE IV GRADE 1 FOLLICULAR LYMPHOMA ANN ARBOR STAGE IV GRADE 2 FOLLICULAR LYMPHOMA ANN ARBOR STAGE IV GRADE 3 FOLLICULAR LYMPHOMA GRADE 3A FOLLICULAR LYMPHOMA