Sound waves and immune shot aim to boost melanoma treatment

NCT ID NCT06472661

First seen Nov 20, 2025 · Last updated May 15, 2026 · Updated 22 times

Summary

This early-phase study tests a new approach for adults with advanced melanoma who are already on immunotherapy and scheduled for surgery. Participants receive focused ultrasound to heat and destroy part of their tumor, plus an injection of an experimental immune-boosting drug called polyICLC directly into the tumor. The goal is to see if this combination is safe and can improve the body's immune response against the cancer.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Virginia

    RECRUITING

    Charlottesville, Virginia, 22908, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.