Sound waves open brain barrier to attack deadly childhood tumor

NCT ID NCT05630209

First seen Nov 01, 2025 · Last updated May 08, 2026 · Updated 18 times

Summary

This study tests whether focused ultrasound can safely open the blood-brain barrier in children with DIPG, a hard-to-treat brain tumor. The goal is to let the chemotherapy drug doxorubicin reach the tumor more effectively. Ten children ages 5 to 21 will be treated, and researchers will monitor side effects and how well the barrier opens.

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Contacts and locations

Locations

  • Children's National Medical Center

    Washington D.C., District of Columbia, 20010, United States

  • Cook Children's Health Care System

    Fort Worth, Texas, 76104, United States

  • Nicklaus Children's Hospital

    Miami, Florida, 33155, United States

Conditions

Explore the condition pages connected to this study.