Sound waves may help chemo reach deadly childhood brain tumors

NCT ID NCT05615623

First seen Apr 25, 2026 · Last updated May 12, 2026 · Updated 3 times

Summary

This early-stage study tests whether focused ultrasound can safely open the blood-brain barrier in children with a rare, aggressive brain tumor called DIPG. The goal is to let the chemotherapy drug doxorubicin reach the tumor more effectively. Ten children aged 5 to 18 who have completed radiation therapy will be enrolled to check safety and how well the barrier opens.

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Contacts and locations

Locations

  • Sunnybrook Research Institute

    Toronto, Ontario, M4N 3M5, Canada

Conditions

Explore the condition pages connected to this study.