New drug cenobamate tested in real life for stubborn seizures

NCT ID NCT06716801

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study is tracking 300 adults with focal epilepsy whose seizures are not well controlled despite trying 2-3 other medications. Researchers are observing how well cenobamate works when added to their current treatment in real-world clinics across France, Germany, and Spain. The main goal is to see how many patients have at least a 50% reduction in seizures after 6 and 12 months of treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Cenobamate (a drug to reduce seizures)
What this could lead to
If successful, this study could show that cenobamate helps more people with hard-to-control focal seizures achieve better seizure control in everyday clinical practice.
What could go wrong
This is an observational study, not a controlled trial, so results may be influenced by other factors. It is also relatively small (300 participants) and early in real-world use, so findings may not apply to everyone.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hôpital TARNIER COCHIN

    RECRUITING

    Paris, France, France

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