Liver cancer radiation trial halted after just one patient

NCT ID NCT02200042

Terminated Disease control Sponsor: NRG Oncology Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study aimed to see if adding focused radiation to standard chemotherapy helps people with a type of liver cancer (intrahepatic cholangiocarcinoma) that cannot be removed by surgery. Only one person enrolled before the trial was stopped early, so no meaningful conclusions can be drawn. The approach combined image-guided radiation with gemcitabine and cisplatin drugs.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

radiation therapy (image-guided radiation therapy)

What this could lead to

If successful, this could show that adding radiation to chemotherapy improves survival for people with liver cancer that cannot be surgically removed.

What could go wrong

The trial was terminated after enrolling only 1 person, so it cannot provide reliable evidence. It is unclear if radiation adds benefit or increases side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cholangiocarcinoma intrahepatic cholangiocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

STAGE III INTRAHEPATIC CHOLANGIOCARCINOMA STAGE IVA INTRAHEPATIC CHOLANGIOCARCINOMA

Contacts and locations

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Locations

Boston Medical Center

Boston, Massachusetts, 02118, United States
Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center

Lebanon, New Hampshire, 03756, United States
Decatur Memorial Hospital

Decatur, Illinois, 62526, United States
Emory University Hospital Midtown

Atlanta, Georgia, 30308, United States
Emory University Hospital/Winship Cancer Institute

Atlanta, Georgia, 30322, United States
FHCC Proton Therapy Center

Seattle, Washington, 98133, United States
Huntsman Cancer Institute/University of Utah

Salt Lake City, Utah, 84112, United States
Indiana University/Melvin and Bren Simon Cancer Center

Indianapolis, Indiana, 46202, United States
Lahey Hospital and Medical Center

Burlington, Massachusetts, 01805, United States
Legacy Good Samaritan Hospital and Medical Center

Portland, Oregon, 97210, United States
Loyola University Medical Center

Maywood, Illinois, 60153, United States
M D Anderson Cancer Center

Houston, Texas, 77030, United States
Maryland Proton Treatment Center

Baltimore, Maryland, 21201, United States
Massachusetts General Hospital Cancer Center

Boston, Massachusetts, 02114, United States
Missouri Baptist Medical Center

St Louis, Missouri, 63131, United States
Mount Sinai Hospital

New York, New York, 10029, United States
Northwestern Medicine Cancer Center Warrenville

Warrenville, Illinois, 60555, United States
Northwestern University

Chicago, Illinois, 60611, United States
OSF Saint Francis Medical Center

Peoria, Illinois, 61637, United States
Ohio State University Comprehensive Cancer Center

Columbus, Ohio, 43210, United States
Piedmont Hospital

Atlanta, Georgia, 30309, United States
Queen's Medical Center

Honolulu, Hawaii, 96813, United States
Sutter Medical Center Sacramento

Sacramento, California, 95816, United States
The Research Institute of the McGill University Health Centre (MUHC)

Montreal, Quebec, H3H 2R9, Canada
University of Alabama at Birmingham Cancer Center

Birmingham, Alabama, 35233, United States
University of Arkansas for Medical Sciences

Little Rock, Arkansas, 72205, United States
University of Cincinnati Cancer Center-UC Medical Center

Cincinnati, Ohio, 45219, United States
University of New Mexico Cancer Center

Albuquerque, New Mexico, 87106, United States
University of Rochester

Rochester, New York, 14642, United States
University of Vermont Medical Center

Burlington, Vermont, 05401, United States
University of Washington Medical Center - Montlake

Seattle, Washington, 98195, United States
University of Wisconsin Carbone Cancer Center - University Hospital

Madison, Wisconsin, 53792, United States
Washington University School of Medicine

St Louis, Missouri, 63110, United States
West Virginia University Healthcare

Morgantown, West Virginia, 26506, United States