Awake and comfortable: new study tests prostate cancer ablation without general anesthesia

NCT ID NCT07412275

Not yet recruiting Symptom relief Sponsor: Koelis Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study will test whether a focal microwave ablation procedure for localized prostate cancer can be performed under local anesthesia instead of general anesthesia or deep sedation. Twenty eligible patients will undergo the treatment while awake, and researchers will measure how often the procedure is completed without needing to switch to stronger anesthesia. The goal is to see if this approach is feasible, safe, and satisfactory for patients.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
microwave ablation and local anesthesia (lidocaine hydrochloride)
What this could lead to
If successful, this approach could make prostate cancer treatment more comfortable and accessible by avoiding general anesthesia.
What could go wrong
This is a very small feasibility study with only 20 participants, so results may not apply widely. The procedure might still require sedation or general anesthesia for some patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hôpital Cochin Port Royal

    Paris, 75014, France

  • Institut Jules Bordet

    Brussels, 1070, Belgium

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