Poop pills for cancer patients? pilot study tests fecal transplants in High-Risk therapies

NCT ID NCT07509450

First seen Apr 07, 2026 · Last updated Jun 19, 2026 · Updated 15 times

Summary

This pilot study is testing whether fecal microbiota transplantation (FMT) — giving processed stool from a healthy donor via enema — is safe and doable in 20 patients with lymphoma or leukemia who are receiving CAR-T therapy or stem cell transplants. The goal is to see if at least half of approached patients join, most stay in the study, and the procedure doesn't cause serious harm. It's an early step to explore if restoring gut bacteria can help these vulnerable patients.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University Health Network

    RECRUITING

    Toronto, Ontario, M5G 2M9, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Fecal microbiota transplant (FMT) enema

What this could lead to

If successful, this could show that FMT is a safe way to restore gut health in patients undergoing intensive cancer therapies, potentially reducing complications.

What could go wrong

This is a very small pilot study with only 20 participants, so results may not apply broadly. There is a risk of serious side effects like infection or bowel injury from the procedure.

Conditions

The condition(s) this trial relates to.

acute myeloid leukemia B-cell non-Hodgkin lymphoma myelodysplastic syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.